A 74-year-old woman presented with a 3-month history of right facial ache radiating to the right forehead and temporal region. Three weeks prior to presentation the left eye became red and irritated and binocular horizontal diplopia developed. CT demonstrated a dilated left superior ophthalmic vein. The patient was referred for neuroophthalmic evaluation. Medical and surgical history included h...

Cosmetic facial filler-related ophthalmic artery occlusion is rare but is a devastating complication, while the exact pathophysiology is still elusive. Cerebral angiography provides more detailed information on blood flow of ophthalmic artery as well as surrounding orbital area which cannot be covered by fundus fluorescein angiography. This study aimed to evaluate cerebral angiographic features...

PURPOSE We tested the hypothesis that the M3 muscarinic acetylcholine receptor subtype mediates cholinergic responses in murine ophthalmic arteries after endothelial removal. METHODS Muscarinic receptor gene expression was determined in ophthalmic arteries with intact and with removed endothelium using real-time PCR. To examine the role of the M3 receptor in mediating vascular responses, opht...

To make clinicians aware of potential sources of error in ophthalmic pharmaceutical clinical trials that can lead to erroneous interpretation of results, a critical review of the study design of various pharmaceutical ophthalmic clinical trials was completed. Discrepancies as a result of study shortcomings may explain observed differences between reported ophthalmic trial data and observed clin...

Corneal transplantation, amniotic membrane transplantation, phacoemulsification cataract extraction, and laser glaucoma therapy are routine ophthalmic surgical procedures in horses. This article discusses the indications, techniques, and postoperative complications of these and other ophthalmic surgical procedures in horses. Meticulous and accurate anatomic repair can minimize postoperative com...

Abstract Maxillary Herpes Zoster (HZ) is rare. Trigeminal HZ most frequently involves the ophthalmic division. Partial or complete ophthalmoplegia is a well-known complication of ophthalmic HZ, and Horner’s syndrome has been previously reported. To our knowledge, simultaneous sixth nerve palsy and Horner’s syndrome complicating maxillary HZ in which the ophthalmic division was spared has not ...

BACKGROUND/AIM Owing to the complex topographical aspects of ophthalmic surgery, teaching with conventional surgical videos has led to a poor understanding among medical students. A novel multimedia three dimensional (3D) computer animated program, called "Ophthalmic Operation Vienna" has been developed, where surgical videos are accompanied by 3D animated sequences of all surgical steps for fi...

Thyroid-associated orbitopathy is a set of ophthalmic symptoms resulting from an autoimmune process in which the swelling of extraocular tissues leads to exophthalmos either caused by hypersecretion and accumulation of glycosaminoglycans in the orbit fibroblasts or being the result of inflammatory processes in the oculomotor. These changes cause eyeball motility disturbances, keratopathy, and t...

INTRODUCTION We present a case of ciprofloxacin-associated pseudotumor cerebri in a 22-year-old African American woman. Withdrawal of ciprofloxacin in our patient resulted in complete resolution of ciprofloxacin-associated pseudotumor, as evidenced by a normal neuro-ophthalmic examination and a cerebrospinal fluid opening pressure of 140 mmH20. CASE PRESENTATION A 22-year-old African American...

In Portugal, the prevalence of human immunodeficiency virus type 2 (HIV-2) seropositivity is higher than in other European countries or North America. Recent literature data points out a possible difference on the pathogenic potential and on the natural history of HIV-1 and HIV-2, suggesting a lower virulence of HIV-2. Facing these hypothesis and the increasing number of HIV-2 cases, we analyse...