We describe the expression pattern of cSix3, a chick homologue of the murine Six3. cSix3 transcripts are expressed from presomitic stages in the most anterior portion of the neural plate. As the neural tube folds and the optic vesicles evaginate, cSix3 is expressed in the optic vesicle and the rostroventral forebrain. At later stages, cSix3 is found in most of the structures derived from the an...

Background. Optic disk melanocytoma is a primary tumor of the optic disk that represents a clinical diagnostic challenge due to its similarities with melanoma. Purpose. The authors present three cases in which genetic expression profiling was used to identify tumor prognosis of optic disk melanocytoma. Case Series. In two cases fine-needle aspiration biopsy was performed to obtain tissue throug...

Aim – To compare the results of optic disc analysis using optical coherence tomography, fundus photography and stereoscopic biomicroscopy. Materials & Methods – A comparative, observational case series and interobserver variability study in which 2 groups of patients were analysed by all the 3 methods. One group had primary open angle glaucoma patients and the other group were patients undergoi...

Purpose: To report two patients with spontaneous scleral perforation and bleb formation associated with Marfan syndrome (MFS); which one of them also showed bilateral optic nerve dural ectasia. Case reports: An 11-year-old girl was referred with progressive myopia. Past medical history was negative. Slit-lamp examination revealed bilateral scleral thinning and perforation with bleb formation, s...

A macro-filter-lens design that can correct for chromatic and geometric aberrations simultaneously while providing for a long focal length is presented. The filter is easy to fabricate since it involves two spherical surfaces and a planar surface. Chromatic aberration correction is achieved by making all the rays travel the same optical distance inside the filter element (negative meniscus). Ge...

Imaging of microand nanofluidics is a challenge since the size of the channels is so small that the installment of additional optical and mechanical switches is very difficult. The size of the device and associated increase in viscous dissipation constitute another constraint. In response to these limitations, this work proposes and demonstrates the manipulation of light by adding a functional ...

A low-cost CCD camera system for imaging Coulter orifices ranging in diameter between 20 μm and 2 mm has been developed and tested. The imaging system incorporates a 6X magnifying lens for viewing the required range of Coulter orifices and LEDs (Light emitting diodes) lamp for back illuminating the orifices. Geometric optic calculations using Zemax® for the micro-lens interfaced with the camera...

A heterogeneous group of conditions can cause changes to the intraocular lens (IOL) during or after implantation in uneventful cataract surgery. We describe a series of 5 patients presenting distinctive deposits on the surface of hydrophilic intraocular lenses, implanted during routine cataract surgery, with a follow-up of 1 to 24 months. Disposable forceps were found to be the source of the pi...

PURPOSE To evaluate how soft lens power affects rigid gas-permeable (RGP) lens power and visual acuity (VA) in piggyback fittings for keratoconus. METHODS Sixteen keratoconus subjects (30 eyes) were included in the study. Piggyback contact lens fittings combining Senofilcon-A soft lenses of -6.00, -3.00, +3.00 and +6.00 D with Rose K2 RGP contact lenses were performed. Corneal topography was ...

OBJECTIVE To describe an optic capture pars plana lensectomy technique. METHODS After core vitrectomy, pars plana lensectomy is performed with preservation of the anterior capsule. Capsulorhexis is performed on the preserved anterior capsule through a 2.8 mm clear corneal incision. An intraocular lens (IOL) is placed in the ciliary sulcus, and then the optic of the IOL is pushed back to the v...