Decubitus ulcers, also known as pressure sores, is a major problem in health care, in particular for patients with spinal cord injuries. These patients cannot feel the discomfort that would urge healthy people to change their posture. We describe a system that uses a sensor mat to detect problematic postures and provides tactile feedback to the user. The results of our preliminary study with he...

Gastric involvement is the least frequent manifestation of Behçet's disease, and effective treatment for it unknown. Here the case of a patient with gastric involvement in Behçet's disease that was markedly improved with adalimumab therapy is presented. A 68-year-old man developed an oral ulcer, erythema, folliculitis, and arthralgia. Behçet's disease was suspected; then, prednisolone and colch...

The present study developed an oral hepatocyte growth factor (HGF) gene therapy strategy for gastric ulcers treatment. An attenuated Salmonella typhimurium that stably expressed high HGF (named as TPH) was constructed, and the antiulcerogenic effect of TPH was evaluated in a rat model of gastric ulcers that created by acetic acid subserosal injection. From day 5 after injection, TPH (1 × 10⁹ cf...

BACKGROUND The roots of Zapoteca portricensis is a common remedy in the treatment gastrointestinal disorders used by tradomedical practitioners in Eastern Nigeria. AIM This study was aimed at evaluating the possible antiulcer activity of the root of this plant in experimental rats. METHODS A methanolic root extract was prepared by cold maceration. Antiulcer activity was tested using absolut...

Herbal medicines appeared promising in prevention of many diseases. This study was conducted to investigate the gastroprotective effect of Curcuma xanthorrhiza leaf in the rats induced gastric ulcer by ethanol. Normal and ulcer control received carboxymethycellulose (5 mL/kg) orally, positive control was administered with 20 mg/kg omeprazole (reference drug) and 2 groups were received 250 mg/kg...

The present study was performed to evaluate the anti-ulcerogenic activity of hyaluronic acid against ethanol induced gastric mucosal injury in rats. Four groups of adult Sprague Dawley rats were orally pretreated respectively with distilled water (ulcer control groups), omeprazole (reference group), high molecular weight hyaluronic acid and 0.8% hyaluronic acid gel (experimental groups) one hou...

Ipomoea Pes-caprae(L.) R.Br (IP)distributed in the tropics and subtropics regions is used in folk and tribal medicines. Traditionally IP was used to treat arthritis, pain, ulcer, cancer and wounds. The present study aims to discover the anti-ulcer effect of ethanolic extract from stems of IP (EESIP) at doses 200 mg/kg & 400 mg/kg in aspirin and pylorus ligature induced gastric ulcer models in t...

A 77-year-old woman was urgently admitted for the treatment of diabetic ketoacidosis and a duodenal ulcer hemorrhage in March 1999. She had a history of diabetes and angina pectoris. After admission, she received oral calcium polystyrene sulfonate and sorbitol to treat hyperkalemia. Nine days later, severe abdominal pain developed. A colonoscopic examination revealed a sigmoid colonic ulcer and...

R aynaud’s phenomenon (RP) with or without digital ulcer formation is a significant cause of morbidity for patients with systemic sclerosis (SSc, scleroderma). Lichtenstein reported oral sildenafil as a treatment of RP for patients with SSc, systemic lupus erythematosus, and idiopathic RP. His report included 10 patients from his community office practice given sildenafil, 50 mg once orally at ...

A 51-year-old man was admitted with an ulcer on the plantar surface of the left foot. The ulcer had appeared 3 weeks earlier, during a trip to the Solomon Islands, in the south-west Pacific Ocean, after he was stung by a shellfish while snorkelling near a reef. Twenty minutes after being stung, the patient experienced pruritus and a burning sensation at the site of sting. Five hours later, an a...