OBJECTIVES To measure the exposure of a group of farmers to organophosphate pesticide in sheep dip, and to record the incidence of symptoms after exposure. DESIGN A prospective study of the autumn 1992 dipping period. Working methods were assessed by questionnaire. Absorption of organophosphate pesticide was estimated before, immediately after, and six weeks after dipping by measuring plasma ...

Children entering classrooms for the first time this fall can be seen carrying backpacks filled with school supplies, yet each new student brings something less obvious but more important—a legacy of their earlier experiences and environment. Three studies published in this issue of Environmental Health Perspectives (Bouchard et al. 2011; Engel et al. 2011; Rauh et al. 2011) deliver compelling ...

Synthetic pesticides are fairly well recognized as a cost-effective method of controlling pests, but these chemicals are toxic to other non-targeted and beneficial species. Pesticides are either directly applied to soil to control soil borne pests or deposited on soil as runoff from their foliar applications and these concentrations are highly enough to effect soil micro-organisms (Bezchlebova ...

Sulprofos, disulfoton, azinphos-methyl, methamidophos, trichlorfon, and tebupirimphos were screened for neurotoxic potential, in accordance with U.S. EPA (FIFRA) requirements. Each organophosphate was administered through the diet for 13 weeks to separate groups of Fischer 344 rats at four dose levels, including a vehicle control. For each study, 12 rats/sex/dietary level were tested using a fu...

Three Low Molecular Weight Fluorescent probes (LMFPs) coumarin-enamine (3a-c) have been synthesized, and their photophysical properties studied in different solvent systems (DMSO, CH3CN, DMF, MeOH, EtOH, Me2CO, MeCO2Et, CHCl3, C6H5Me, C6H6). Dimethyl sulfoxide was chosen as the optimum to investigate 3a for organophosphate detection. On deprotonation of oxime, a significant spectroscopic shift ...