The ORF74 or vGCR gene encoded by Kaposi's sarcoma-associated herpesvirus (KSHV; also called human herpesvirus 8) has properties of a ligand-independent membrane receptor signaling protein with angiogenic properties that is predicted to play a key role in the biology of the virus. We have examined the expression of vGCR mRNA and protein in primary effusion lymphoma (PEL) cell lines, PEL and mul...

Dielectric energy-storage capacitors are among the main enabling technologies in high-density power converters, which lead-free relaxor ferroelectric ceramics have been paid particular attention to. However, low performance at elevated temperature and high electric field, lack of application-oriented evaluation primary blocks stumbling their progress. As a demonstration, 0.87BaTiO3-0.13Bi[Zn2/3...

Riemann's minimal surfaces, a one-parameter family of minimal surfaces, describe a bicontinuous lamellar system with pores connecting alternating layers. We demonstrate explicitly that Riemann's minimal surfaces are composed of a nonlinear sum of two oppositely handed helicoids.

During cycling between the tick vector and a mammal, the Lyme disease spirochaete Borrelia burgdorferi must coordinate expression of outer-surface proteins (Osps) A and B to quickly respond to environmental changes. The pathogen abundantly produces OspA/B in the tick, but represses their expression during mammalian infection. This paper reports a regulatory structure, consisting of two sequence...

A well-known precursor of an imminent solar eruption is the appearance a hot S-shaped loop, also known as sigmoid, in active region (AR). Classically, formation such loop envisaged to be implemented by magnetic reconnection two oppositely oriented J-shaped loops. However, details are elusive due weak emission and subtle evolution during pre-eruptive phase. In this paper, we investigate how sing...

How food and water intake is reciprocally regulated to maintain homeostasis is unclear. New findings by Jourjine and colleagues identify four neurons in the Drosophila brain that receive both water and sugar abundance signals and oppositely regulate hunger and thirst.

Individual spindle fibres in prometaphase spermatocytes of the cricket, Neocurtilla hexadactyla, were irradiated with an ultraviolet microbeam. The stretched heteromorphic bivalent (X2Y) contracted to about 75% of its pre-irradiation length after irradiation of either of its two oppositely directed spindle fibres (i.e., the X2 or Y spindle fibre). The X2Y bivalent also contracted after irradiat...

In this issue of Neuron, Mure et al. (2016) demonstrate that two mechanisms-phosphorylation of a C-terminal intracellular region, and mechanism involving the whole of the C terminus-oppositely shape the kinetics and sensitivity of the nonvisual photoreceptor melanopsin.

Translocating solution-phase molecular recognition of oppositely charged hosts and guests to the solid phase represents a major challenge; we report a successful immobilisation strategy which allows selective host-guest interactions in water unencumbered by unwanted ion exchange-type interactions.

Objective(s):  It is proposed that particulate antigens could better interact with the antigen presenting cells (APCs). A fast, simple and scalable process for preparation of polymeric nanoparticles (NPs) is coating of charged antigenic particles, like viruses, with oppositely charged polymers. A second coating with a charged polymer could increase the stability and modify the immunomodulatory ...