Introduction: Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnost...

we report an unusual case of hemimegalencephaly (hmg) associated with ipsilateral congenital-infiltrating lipomatosis of the face in a five-month-old boy. hemimegalencephaly is a rare but unique malformation characterized by enlargement of all or parts of a cerebral hemisphere. the affected hemisphere may have focal or diffuse neuronal migration defects, with areas of polymicrogyria, pachygyria...

OBJECTIVES To analyze the frequency and type of benign orofacial lesions submitted for diagnosis at Tripoli Medical Centre over 17 years period (1997-2013). MATERIALS AND METHODS Entries for specimens from patients were retrieved and compiled into 9 diagnostic categories and 82 diagnoses. RESULTS During the 17 years period, a total of 975 specimens were evaluated, it comprised a male-female...

Interaction between covert and overt orofacial gestures has been poorly studied apart from old and rather qualitative experiments. The question deserves special interest in the context of the debate between auditory and motor theories of speech perception, where dual tasks may be of great interest. It is shown here that dynamic mandible and lips movement produced by a participant result in stro...

Neurofibromatosis type 1 (NF1) is a relatively frequent mucocutaneous syndrome, which is transmitted as an autosomal dominant trait or which may represent neomutation. It is characterized by a variety of clinical manifestations, including multiple neurofibromas that are associated with a high risk of sarcomatous transformation. The aim of this report was to elucidate the orofacial manifestation...

UNLABELLED Clinical differentiation between the primary headaches and temporomandibular disorders (TMD) can be challenging. OBJECTIVES To investigate the relationship between TMD and primary headaches by conducting face to face assessments in patients from an orofacial pain clinic and a headache tertiary center. METHOD Sample consists of 289 individuals consecutively identified at a headach...

BACKGROUND Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common congenital malformation among live births, and depends on race and ethnic background. The CDH1 gene plays a vital role in orofacial development. Our research was conducted to examine the association between 3 single-nucleotide polymorphisms in the CDH1 gene and NSCL/P. METHODS Three single-nucleotide polymorph...

gastrointestinal (gi) bleeding in pediatric patients has several causes. vascular malformation of the small bowel is a rare disease leading to pediatric gi bleeding. to our knowledge, few reports describe ultrasound and computed tomography findings of venous malformations involving the small bowel. we present a case of long-segmental and circumferential vascular malformation that led to gi blee...

the teratogenicity of cadmium exposure was studied in virgin nimri rats aged 10-13 weeks. pregnant animals were fed cadmium sulfate equivalent to doses of 1,4 and 7 mg/kg/day of cadmium by oral gavage on the day 7 of gestation. on the day 18 of gestation, fetuses were delivered and examined for external and skeletal malformations. total percent of malformed fetuses in rats treated by different ...

Mammals perform a multitude of well-coordinated orofacial behaviors such as breathing, sniffing, chewing, licking, swallowing, vocalizing, and in rodents, whisking. The coordination of these actions must occur without fault to prevent fatal blockages of the airway. Deciphering the neuronal circuitry that controls even a single action requires understanding the integration of sensory feedback an...