BACKGROUND To investigate the effectiveness of orthokeratology (ortho-k) in reducing the development of myopia in Chinese children with low to moderate myopia. METHODS This was a retrospective study. In the ortho-k group, there were141 subjects, and the average age was (9.43 ± 1.10) years. The average spherical equivalent refractive error (SER) was (-2.74 ± 1.15)D, with examinations performed...

Estrogenic and thyroid activities of 91 monohydroxylated PCBs were measured with two-hybrid assays using yeast cells containing the human estrogen receptor ERalpha or human thyroid receptor TRalpha. Estrogenic activity of 30 of the 91 compounds, including all compounds active in the yeast two-hybrid assay, were also measured by a reporter gene assay employing Chinese hamster ovary cells. The ma...

BACKGROUND Exposure to persistent organic pollutants (POPs) such as dioxins, furans, and polychlorinated biphenyls (PCBs) may influence leukocyte telomere length (LTL), a biomarker associated with chronic disease. In vitro research suggests dioxins may bind to the aryl hydrocarbon receptor (AhR) and induce telomerase activity, which elongates LTL. However, few epidemiologic studies have investi...

Background and Aim: This study aimed to evaluate the effect of repeated bonding by self-etching primers (SEPs) and a conventional phosphoric acid-etchant on shear bond strength (SBS), adhesive remnant index (ARI), and enamel morphology at different debonding time points. Materials and Methods: In this experimental study, 120 premolars were randomly divided into six groups of 20. In the first t...

The mono ortho-bromination of phenolic building blocks by NBS has been achieved in short reaction times (15-20 min) using ACS-grade methanol as a solvent. The reactions can be conducted on phenol, naphthol and biphenol substrates, giving yields of >86% on gram scale. Excellent selectivity for the desired mono ortho-brominated products is achieved in the presence of 10 mol % para-TsOH, and the r...

Rapid and catalyst-free hydrazone ligation reaction between ortho-halobenzaldehyde derivatives and peptide/protein hydrazides was observed at neutral pH and room temperature. 2-Chlorobenzaldehyde exhibited the fastest reaction and highest conversion rates among the series of ortho-halobenzaldehydes. The resulting hydrazone-containing bioconjugation products were also found to be fairly stable u...

4 Department of Bioengineering, Stanford University, Stanford, CA 94305, USA #: Corresponding authors: Prof. Nidhi Bhutani, Ph.D. Prof. Fan Yang, Ph.D. Department of Ortho. Surg. Departments of Ortho. Surg. and Bioeng. 300 Pasteur Dr. , Edwards R164 300 Pasteur Dr., Edwards R105 Stanford, CA 94305-5341 Stanford, CA, 94305-5341 Tel: 650 721 2234 Tel: 650 725 7128 Fax: 650 723 9370 Fax: 650 723 9...