نتایج جستجو برای: oscillatory shear index
تعداد نتایج: 484394 فیلتر نتایج به سال:
Aortic valve (AV) calcification is an inflammation driven process that occurs preferentially in the fibrosa. To explore the underlying mechanisms, we investigated if key microRNAs (miRNA) in the AV are differentially expressed due to disturbed blood flow (oscillatory shear (OS)) experienced by the fibrosa compared to the ventricularis. To identify the miRNAs involved, endothelial-enriched RNA w...
Rheological material functions are used to form our conceptual understanding of a material response. For a nonlinear rheological response, the possible deformation protocols and material measures span a high-dimensional space. Here we use asymptotic expansions to outline lowdimensional measures for describing leading-order nonlinear responses in large-amplitude oscillatory shear (LAOS). These i...
Connexins are proteins forming gap junction channels for intercellular communication. Connexin40 (Cx40) is highly expressed by endothelial cells (ECs) of healthy arteries but this expression is lost in ECs overlying atherosclerotic plaques. Low/oscillatory shear stress observed in bends and bifurcations of arteries is atherogenic partly through activation of the pro-inflammatory NFκB pathway in...
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