PURPOSE Talc pleurodesis (TP) is employed worldwide for the management of persistent pneumothorax or pleural effusion, particularly of malignant origin. However, there are very little available data on (18)F-fluorodeoxyglucose positron-emission tomography/computed tomography ((18)F FDG PET/CT) response evaluation in malignant pleural mesothelioma (MPM) patients treated with TP and chemotherapy....

List-mode processing is an efficient way of dealing with the sparse nature of PET data sets, and is the processing method of choice for time-of-flight (ToF) PET. We present a novel method of computing line projection operations required for list-mode ordered subsets expectation maximization (OSEM) for fully 3-D PET image reconstruction on a graphics processing unit (GPU) using the compute unifi...

Purpose A pinhole collimator is routinely used to increase the resolution of scintigraphy. This prospective study was conducted to determine the interest of Tc-MIBI pinhole SPECT for the preoperative localization of parathyroid lesions in primary hyperparathyroidism. Methods All patients underwent a neck US, TcO4 and Tc-MIBI planar images, and two consecutive SPECT with a parallel (C-SPECT) and...

The nondestructive testing (NDT) of long object (such as pipeline) has significant value. Computed tomography (CT) is able to generate 3D images and display the inner defects of the inspected object. Sometimes the long object fixed outdoors can’t be rotated, and the rotating of the X-ray source and detector is also difficult. So the linear scan CT, translating the X-ray source and detector alon...

Methods: A uniform Ge-68 phantom (20 cm diameter and length) was imaged on a D-RX PET/CT scanner twice; once with all detectors operational (baseline) and once with 5 detector elements at each of 0, 90, 180 and 270 degrees turned off (partially sampled). The partially sampled (PS) sinogram was first decomposed into two different layers – cartoons and texture using Daubechie wavelets (6rh order)...

Prior reports have suggested that delayed FDG-PET oncology imaging can improve the contrast-to-noise ratio (CNR) for known lesions. Our goal was to estimate realistic bounds for lesion detectability for static measurements with one to four hours between FDG injection and image acquisition. Tumor and normal tissue kinetic model parameters were estimated from dynamic PET studies of patients with ...

Tomographic SPECT allows us to visualize, in 3D, the distribution of radiopharmaceuticals in the body which are reconstructed from a series of two dimensional measurements performed around the investigated object. The dSPECT method extends these capabilities into the fourth dimension and creates a series of dynamic 3D images which can be obtained from a single set of dynamic data acquired using...

Quantitative positron emission tomography (PET) using statistical techniques requires: d̂flk..»;„-.IK:. system geometric model that represents the probability of detecting an emission from each impgf. , pixel at each detector-pair, and (b) an iterative algorithm that reconstructs image as quaatitativfi , tt. measurements of radiotracer distribution in vivo. Conventional implementations of iterat...

We have investigated statistical list-mode reconstruction applicable to a depth-encoding high resolution research tomograph. An image non-negativity constraint has been employed in the reconstructions and is shown to effectively remove the overestimation bias introduced by the sinogram non-negativity constraint. We have furthermore implemented a convergent subsetized (CS) list-mode reconstructi...