Titanium implants are widely used in orthopaedic and dental surgery. Surface properties play a major role in cell and tissue interactions. The adhesion and differentiation of mesenchymal stem cells were studied as a function of nanostructures. Titanium surfaces with nanopores 30, 150 and 300 nm in diameter were prepared by physical vapour deposition. PCR arrays indicated that the expression of ...

Osteopoikilosis is a rare, benign osteosclerotic dysplasia that predominantly involves the appendicular skeleton. Radiographic findings are diagnostic, and the disease often is discovered incidentally on x-ray films. The importance of recognizing osteopoikilosis lies in differentiating it from osteoblastic metastases. The cause is unclear. Patients typically are asymptomatic. Diagnostic finding...

The proliferation-differentiation behaviour of human alveolar bone cell cultures grown for 32 days in conditions that allowed the complete expression of the osteoblastic phenotype was significantly affected by the continuous presence of parathyroid hormone, 1, 25-dihydroxyvitamin D(3), or dexamethasone. Parathyroid hormone and, in particular, dexamethasone significantly induced the differentiat...

Aims At the histological level, the differential diagnosis of osteoblastic bone tumors is characterized by several problems that cannot be solved by conventional histological methods, including immunohistology. Differentiating aneurysmal bone cyst from telangiectatic osteosarcoma or giant cell tumor from giant cell-containing highly malignant osteosarcoma are only two examples reflecting the co...

One new (4) and twelve known phenolic compounds (1-3, 5-13) were isolated from a 70% MeOH extract of the aerial parts of Artemisia iwayomogi. The new compound was identified as 7,8-dimethoxy-coumarin-9-O-(6'-O-(E)-coumaroyl)-beta-D-glucopyranoside (4) and named iwayomin. The effects of compounds 1-13 on the function of osteoblastic MC3T3-E1 cells were examined by evaluating cell viability, alka...

objective: biodegradable polycaprolactone/starch composites can be used for bone tissue engineering applications. the effect of the ratio of components on composite properties is of tremendous importance. methods: polycaprolactone/starch composite of 80/20 and 70/30 ratios were fabricated by dissolving them in chloroform followed by evaporation of the solvent. results: the composites were chara...