Background. At present, FRAX is a well-known and widely-used risk assessment tool for major osteoporotic fractures. The Ukrainian version of the algorithm was presented in 2016; with “intervention threshold” additional DXA examination antiosteoporotic treatment women published 2019. However, data on its possible uses men are limited. purpose study to evaluate possibilities using previously deve...

Osteoporosis results in significant morbidity and medical costs while effective treatment options are also evolving. Bisphosphonates are considered standard antiosteoporotic medication. Other antiresorptive treatment options of osteoporosis include selective oestrogen receptor modulators, hormone therapy, calcitonin, and denosumab. In addition, strontium ranelate of dual mechanism (anabolic and...

While knowledge regarding the diagnosis and treatment of osteoporosis has expanded dramatically over the last few years, gaps in knowledge still exist with guidance lacking on the appropriate management of several common clinical scenarios. This article uses fictional clinical scenarios to help answer three challenging questions commonly encountered in clinical practice. The first clinical chal...

In an effort to step up fracture prevention efforts, the National Osteoporosis Foundation (NOF) has released a revised guide on the comprehensive management of osteoporosis, which includes detailed recommendations on assessment and diagnosis, in addition to a summation of treatment options. This article includes updated NOF recommendations, pharmacoeconomic considerations of assessing fracture ...

1 for greater awareness and improved management of patients suffering from osteoporosis or osteopenia and those with fragility fractures, particularly the elderly. We contend that this disease is not optimally managed locally and is often still regarded as an inevitable part of the ageing process, not amenable to treatment. The facts that 20% of hip fracture victims die within one year of the e...

Osteoporosis -related to various factors including menopause and aging- is the most common chronic metabolic bone disease, which is characterized by increased bone fragility. Although it is seen in all age groups, gender, and races, it is more common in Caucasians (white race), older people, and women. With an aging population and longer life span, osteoporosis is increasingly becoming a global...

The number of women with osteoporosis, ie, with reduced bone mass and the disruption of bone architecture, is increasing in India. While data on prevalence of osteoporosis among women in India come from studies conducted in small groups spread across the country, estimates suggest that of the 230 million Indians expected to be over the age of 50 years in 2015, 20%, ie, ~46 million, are women wi...

Management of cirrhosis complications has greatly improved, increasing survival and quality of life of the patients. Despite that, some of these complications are still overlooked and scarcely treated, particularly those that are not related to the liver. This is the case of osteoporosis, the only cirrhosis complication that is not solved after liver transplantation, because bone loss often inc...

There has been substantial progress in the management of patients with osteoporosis and the prevention of osteoporotic fractures. Currently available strong anti-resorptive agents are bisphosphonates and an anti-receptor activator of nuclear factor-kappa B ligand (RANKL) antibody, denosumab. Although bisphosphonates and denosumab both inhibit bone resorption and prevent vertebral and non-verteb...