T he immune system appears to be rigid, restricting one lymphocyte to make one antibody (1) and the peripheral B cell pool to a constant number (10 8 in mice) (2– 4). To make a rapid immune response to an unlimited number of antigens at any anatomical site, it has developed at least three major strategies: (a) continuous production of 2 ϫ 10 7 lymphocytes/d from bone marrow (mice; 5), displayin...

BACKGROUND Detailed fluorescein angiographic findings in the disc circumference may be useful for evaluating the possible relation of the circumference to glaucomatous nerve damage. METHODS Fluorescein angiograms of 25 eyes of 25 subjects with primary open angle glaucoma were observed after they had undertaken Octopus perimetry. Based on the retinotopic projection, disc sectors and correspond...

We describe the use of a commercial e-beam lithography system (JEOL JBX-6000FS) to fabricate Fresnel zone plates for x-ray microscopy. The machine is capable of controlling the pitch of optical gratings with sub-nanometer precision, so its beam placement properties are more than adequate for zone plate fabrication. The zone plate pattern is written into a thin top layer (PMMA or Calixarene) of ...

In this paper, we propose a structure for organo-mineral associations in soils based on recent insights concerning the molecular structure of soil organic matter (SOM), and on extensive published evidence from empirical studies of organo-mineral interfaces. Our conceptual model assumes that SOM consists of a heterogeneous mixture of compounds that display a range of amphiphilic or surfactant-li...

LEE, JAMES B., AND HELEN M. PETER. Effect of oxygen tension on glucose metabolism in rabbit kidney cortex and medulla. Am. J. Physiol. 217(5) : 1464-1471. 1969.-Slices of rabbit renal cortex, outer medulla, outer papilla, and papillary tip were incubated in KrebsRinger bicarbonate buffer containing glucose-UJ4C, 10 II~M. Incremental increases in medium POT from 32 to 530 mm Hg resulted in a ste...

The Earth's core is mostly an Fe-Ni alloy with a fraction of light elements (~10 wt%, mainly O, S and Si). Accumulation of these light elements under the core-mantle boundary (CMB) may lead to chemical stratification. Seismic observations have been presented both for and against the stratification in the topmost region of the outer core. Here we investigate the structure under the CMB using dif...

Purpose To report an anti-recoverin antibody-positive cancer-associated retinopathy (anti-recoverin CAR) patient with remarkable improvements of visual function and outer retinal morphology following spontaneous regression of cancer. Observations A 65-year-old woman with small cell lung carcinoma developed progressive, bilateral vision loss with diffuse loss of the ellipsoid zone at the macul...

We have investigated whether Earth-mass planets could survive in the habitable zone (HZ) of the 47 Ursae Majoris system. Mixed-variable symplectic numerical integration has been used to investigate the orbits of putative Earth-mass planets. Whereas the 47 UMa system as previously known, with just one giant planet, could have Earth-mass planets that remain confined to the HZ for a fairly wide ra...