نتایج جستجو برای: ovarian development

تعداد نتایج: 1489267  

2013
Dmitry Fridman Muhammad Faisal Aslam Neekianund Khulpateea

Background: Radiographic studies largely contribute to prompt diagnosis of ovarian torsion, though postoperative changes are not described and might contribute to unnecessary intervention. Case: We report a case of ovarian torsion diagnosed based on clinical presentation and radiographic findings. The detorsion was successfully performed through laparosopic access. Subsequently patient presente...

2015
Jianguo Hu Ying Meng Tinghe Yu Lina Hu Ming Mao

Ubiquitin E3 ligase MARCH7 is involved in T cell proliferation and neuronal development. We found that expression of MARCH7 was higher in ovarian cancer tissues than normal ovarian tissues. Silencing MARCH7 decreased cell proliferation, migration, and invasion. Ectopic expression of MARCH7 increased cell proliferation, migration and invasion. Silencing MARCH7 prevented ovarian cancer growth in ...

2015
T. Baert D. Timmerman I. Vergote A. Coosemans

Ovarian cancer is the leading cause of pelvic gynecological cancer death in Europe. Prognosis is poor in women diagnosed at stage III to IV or in case disease recurs. Platin-based chemotherapy and radical surgery have already improved prognosis significantly. Novel strategies in the treatment of ovarian cancer are being searched for. The study of the immune system as a valuable parameter in the...

Journal: :Human reproduction update 2007
M L Hendriks J C F Ket P G A Hompes R Homburg C B Lambalk

Polycystic ovary syndrome (PCOS) is a complex disorder with heterogeneity of clinical and endocrine features. Ovarian surgery for ovulation induction has been used in the management of clomiphene citrate-resistant anovulatory women with PCOS. Various types of ovarian surgery have been employed (wedge resection, electrocautery, laser vaporization, multiple ovarian biopsies and others) and all pr...

2010
Saneal Rajanahally Julio E Agno Roopa L Nalam Michael B Weinstein Kate L Loveland Martin M Matzuk Qinglei Li

BACKGROUND Inhibin is a tumor-suppressor and activin antagonist. Inhibin-deficient mice develop gonadal tumors and a cachexia wasting syndrome due to enhanced activin signaling. Because activins signal through SMAD2 and SMAD3 in vitro and loss of SMAD3 attenuates ovarian tumor development in inhibin-deficient females, we sought to determine the role of SMAD2 in the development of ovarian tumors...

Journal: :Reproduction 2008
Gretchen Dole Eric E Nilsson Michael K Skinner

Female fertility is determined in part by the size and development of the primordial follicle pool. The current study investigates the role of glial cell-line-derived neurotrophic factor (GDNF) in the regulation of primordial follicle development in the ovary. Ovaries from 4-day-old female rat pups were maintained in organ culture for 10 days in the absence (control) or presence of GDNF or kit ...

2015
Minli YU Yali XU Defu YU Debing YU Wenxing DU

Many genes participate in the process of ovarian germ cell development, while the combined action mechanisms of these molecular regulators still need clarification. The present study was focused on determination of differentially expressed genes and gene functions at four critical time points in chicken ovarian development. Comparative transcriptional profiling of ovaries from embryonic day 5.5...

Journal: :Arquivos brasileiros de endocrinologia e metabologia 2011
Bashir Ahmad Laway Syed Tufail Mir Iftikhar Bashir Mohd Ashraf Ganie Abdul Hamid Zargar

Premature ovarian failure has an overall prevalence of 0.3% to 0.9% in general population. If fertility is a concern, treatment usually consists of estrogen therapy as hormone replacement and oocyte donation. Spontaneous pregnancy in affected women is uncommon. We report a case of a 34-year old woman, who had premature ovarian failure and primary hypothyroidism, and conceived spontaneously elev...

Journal: :Cancer research 2009
Blanca Herrera Maarten van Dinther Peter Ten Dijke Gareth J Inman

Bone morphogenetic proteins (BMPs) act as central regulators of ovarian physiology and may be involved in ovarian cancer development. In an effort to understand these processes, we characterized transforming growth factor beta/BMP receptor and Smad expression in immortalized ovarian surface epithelial cells and a panel of ovarian cancer cell lines. These studies prompted us to evaluate the pote...

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