Printed by Summary It is believed that endometriosis has significant damaging effect on ovarian reserve. With regards to the effect of endometrioma on AMH levels, currently available evidence provides conflicting views; ranging significantly lower AMH measurements in smaller studies, to no association between AMH and endometrioma in more robust studies (Uncu et. al. 2013, Hwu et. al. 2013, Stre...

As the chronological age increases, there is a physiological decline in reproductive potential of women. Moreover, the chronological age of women may not reflect the biological age of her ovaries. Various endocrine markers have been used to assess the ovarian reserve. The changing pattern of the endocrine markers; follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2) and ...

A prospective measurement of follicle stimulating hormone (FSH) and oestradiol between cycle days 2 and 5 was conducted to investigate the intra- and inter-cycle variability in a healthy population of women with regular menstrual intervals. Daily serum samples were obtained from 44 women for a total of 66 cycles on cycle days 2, 3, 4 and 5. FSH concentrations were consistent on all cycle days m...

The human ovary is a dynamic organ which continually changes in size and activity through life, as an integral part of the changes that the female is going through before during and after her reproductive life. Following the rapid increase in the use of transvaginal scan in recent years, the measurement of ovarian volume has become quick, accurate and cost-effective. Ovarian volume is an import...

BACKGROUND Anti-Müllerian hormone (AMH) is an established marker of ovarian reserve and a good predictor of poor or excessive ovarian response after controlled hyperstimulation. However, it is unclear whether it can predict the ultimate outcome of assisted conception, live birth. We undertook a systematic review and meta-analysis to examine whether AMH is a predictor of live birth in women unde...

CONTEXT Whether infertile women exhibit accelerated ovarian aging and whether a low ovarian reserve is overrepresented in infertility populations is not known. OBJECTIVE To compare the age-related decline in antral follicle count (AFC), a biomarker of the ovarian reserve, in fertile and infertile women. DESIGN Cross-sectional data from a large prospective cohort study conducted from January...

BACKGROUND Phthalates, a class of endocrine disruptors, have been demonstrated to accelerate loss of ovarian follicle pool via disrupting folliculogenesis, and lead to diminished ovarian reserve. However, human data are limited. Here, we aimed to examine whether urinary phthalate metabolites are correlated with markers of ovarian reserve among women attending a fertility clinic. METHODS We me...