Background Lingual dystonia is a subtype of oromandibular dystonia, which is a movement disorder characterized by involuntary sustained or intermittent contraction of the masticatory and/or tongue muscles. Lingual dystonia interferes with important daily activities, such as speaking, chewing, and swallowing, resulting in vocational and social disability. Objective The aim of this study was to...

Three recent reports, including one in this issue of Cell, reveal that the circadian regulator CRY is targeted for degradation by the F box E3 ubiquitin ligase FBXL3 (Siepka et al., 2007; Busino et al., 2007; Godinho et al., 2007). These studies confirm the importance of targeted protein degradation as a key design feature of the mammalian circadian clock.

We propose an extended maintenance overtime policy for the cumulative damage model where an operating unit suffers some damage due to shocks. It is assumed that the total damage is additive, and the unit fails when the total damage has exceeded a prespecified damage level. It is supposed that we start to observe occurrence of shocks after time T, and the unit is replaced at Nth (N = 1, 2, ...) ...

Working from home (WFH) can be a challenge as well especially in third world countries due to economic constrains some people cannot afford gadgets and internet. Women are not spared they involved multi-task. Drawing employee isolation literature, this paper aimed examine the impact of working on female employees during imposed lockdown. Qualitative research was employed in-depth interviews wit...