Ovulation in Caenorhabditis elegans requires inositol 1,4,5-triphosphate (IP(3)) signaling activated by the epidermal growth factor (EGF)-receptor homolog LET-23. We generated a deletion mutant of a type I 5-phosphatase, ipp-5, and found a novel ovulation phenotype whereby the spermatheca hyperextends to engulf two oocytes per ovulation cycle. The temporal and spatial expression of IPP-5 is con...

The rate of ovulation of the domestic fowl may be expressed by the equation of an autocatalytic chemical reaction. This is not surprising in view of the fact that the rate of growth may also be expressed by such an equation, and that the rate of ovulation is probably an index of the growth of the eggs. This brings the phenomenon of ovulation in the hen under the general subject of growth, and s...

I will be using the term anovular in this presentation. This means that a cow is not ovulating. Some people prefer the term anestrus. This means a cow is not showing heat or may not be cycling. We are generally evaluating the ovaries in our studies and so we can accurately tell which cows are ovulating but not showing heat and which cows are not ovulating whether or not they are showing heat. I...

The purpose of this paper was to evaluate the anti-ovulatory effects of indomethacin, aspirin and melatonin by examining the LH sensitive 13,14-dihydroprostaglandin F2 alpha forming capacity in rat ovary. When ovulation was blocked by aspirin or melatonin, the forming capacity was strongly suppressed, and these effects were reversed by hCG injection. However, the ovulation blockage by indometha...

This review will focus on the main findings of our experiments that used B-mode and color-Doppler ultrasonography during the preovulatory period to study the morphological and blood flow/perfusion changes of the preovulatory follicle in mares. The topics to be addressed herein will be: ultrasonographic characteristics of the preovulatory follicle; B-mode echotextural changes of the follicle wal...

Developing successful methods for synchronizing estrus and ovulation in cattle has been a major research interest for at least the last 35 yr. Early objectives focused on the control of the corpus luteum (CL) and artificial insemination (AI) relative to estrus. Ultimately, the goal has been to achieve precise synchronization of ovulation so that cattle can be inseminated without regard to estru...

■ EVIDENCE-BASED ANSWER Short-term use of metformin (Glucophage) improves ovulation rates for women with polycystic ovary syndrome (PCOS) (strength of recommendation [SOR]: A, based on systematic reviews of randomized controlled trials [RCT]). Metformin also decreases menstrual irregularities (SOR: B, extrapolated from a systematic review). When added to clomiphene, metformin increases ovulatio...

The most well-known biological theory is that women feel their sex drive kick into highest gear during ovulation at mid-cycle, approximately 14 days before they get their next period. The surge in estrogen and the added testosterone bonus that accompany ovulation explain why some women experience heightened libido during this time. This change makes logical sense when viewed within the context ...

Oestradiol enhances pituitary sensitivity to gonadotrophin-releasing hormone (GnRH) in normal women, while in women undergoing ovulation induction the putative factor gonadotrophin surge attenuating factor (GnSAF) attenuates the response of luteinizing hormone (LH) to GnRH. To study the relationships between oestradiol and GnSAF during ovulation induction, 15 normally ovulating women were inves...