نتایج جستجو برای: oxa michael reaction

تعداد نتایج: 437231  

A new and efficient method has been developed for the synthesis of 4-aryl-7-benzylidene-1,3,4,5,6,7-hexahydro-2H-cyclopenta[d]pyrimidin-2-ones through Biginelli-like reaction of cyclopentanone, with urea/thiourea and aromatic aldehyde employing p-dodecylbenzenesulfonic acid (DBSA) as a recyclable catalyst under solvent-free condition. The recovered catalyst was recycled for further runs. The pr...

2011
Ke Wang Lina Liu Tao Zhang Yong-liang Zhu Fuming Qiu Xian-guo Wu Xiao-lei Wang Fu-qiang Hu Jian Huang

PURPOSE The failure of cancer treatments is partly due to the enrichment of cancer stem-like cells (CSLCs) that are resistant to conventional chemotherapy. A novel micelle formulation of oxaliplatin (OXA) encapsulated in chitosan vesicle was developed. The authors postulate that micelle encapsulation of OXA would eliminate both CSLCs and bulk cancer cells in colorectal cancer (CRC). EXPERIMEN...

Journal: :Cell metabolism 2016
Sebastian B Stiller Jan Höpker Silke Oeljeklaus Conny Schütze Sandra G Schrempp Jens Vent-Schmidt Susanne E Horvath Ann E Frazier Natalia Gebert Martin van der Laan Maria Bohnert Bettina Warscheid Nikolaus Pfanner Nils Wiedemann

The mitochondrial inner membrane harbors three protein translocases. Presequence translocase and carrier translocase are essential for importing nuclear-encoded proteins. The oxidase assembly (OXA) translocase is required for exporting mitochondrial-encoded proteins; however, different views exist about its relevance for nuclear-encoded proteins. We report that OXA plays a dual role in the biog...

Journal: :Acta Biochimica et Biophysica Sinica 2021

Oxaliplatin (OXA) resistance limits the efficiency of treatment for hepatocellular carcinoma (HCC). Studies have shown that PDZ-binding kinase (PBK) plays important roles in tumors. However, role PBK HCC is still a problem. In this study, we explored whether involved chemoresistance to OXA HCC. Expressions six cell lines and one human hepatocytes line were determined by real-time quantitative P...

Journal: :مجله بین المللی علوم آزمایشگاهی 0
samere kiani hassan momtaz amir arsalan serajian elahe tajbakhsh

background and aims: acinetobacter baumannii is regarded as an important nosocomial pathogen around the world, especially in the intensive care unit that today seems to be resistant to the most antibiotics. therefore, this study aimed to trace classes 1, 2, and 3 integrin in the isolates resistant to acinetobacter baumannii. materials and methods: in this descriptive study, acinetobacter bauman...

Journal: :The Journal of the Society of Chemical Industry, Japan 1954

2014
Fabrice Compain Dominique Decré Isabelle Frazier Astrid Ramahefasolo Marie Lavollay Etienne Carbonnelle Hidayeth Rostane Arzu Tackin Anne Berger-Carbonne Isabelle Podglajen

Technical Appendix Table. β-lactamase profiles of multidrug-resistant Gram-negative bacilli isolated in 2010 and 2011, France* Region of origin No. culture-positive patients/total no. patients Species No. isolates β-lactamase ESBL Carbapenemase pCASE Africa 33/87 E. coli 18 CTX-M-15 2 CTX-M-1 2 SHV-12 1 CTX-M-3 OXA-48 1 CTX-M-14 1 CTX-M-15 TEM-169 1 CTX-M-15 CMY-2 1 CTX-M-24 OXA-48 1 ND K. pneu...

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