Polyphenol-rich grape seeds have a beneficial effect on human health. The present study was performed to investigate the effects of grape seeds on antioxidant activities in rats. Male Sprague-Dawley rats were randomly divided into a control diet group (C), a high-fat diet group (HF), a 5% grape seed-supplemented control diet group (G), and a 5% grape seed-supplemented high-fat diet group (HG). ...

High dietary fat intake leads to insulin resistance in skeletal muscle, and this represents a major risk factor for type 2 diabetes and cardiovascular disease. Mitochondrial dysfunction and oxidative stress have been implicated in the disease process, but the underlying mechanisms are still unknown. Here we show that in skeletal muscle of both rodents and humans, a diet high in fat increases th...

background: koobideh kebab (barbequed minced meat) is one of the most popular iranian foods. reduction in the water holding capacity (whc) of meat during thermal processing makes the water and melted fat run out of the meat. the fat content of the final product depends on the proportion of the retained moisture and fat. meanwhile, high temperature and the presence of oxygen and iron in meat may...

The present article addresses the hypothesis that disturbances in skeletal muscle fatty acid handling in abdominal obesity and type 2 diabetes mellitus may play a role in the aetiology of increased adipose tissue stores, increased triacylglycerol storage in skeletal muscle and skeletal muscle insulin resistance. The uptake and/or oxidation of fatty acids have been shown to be impaired during po...

Considerable experimental evidence suggests that lipid peroxides on LDL and their breakdown products are responsible for the physical changes in the LDL particle and the fragmentation of its apolipoprotein B, which permit it to bind to a wide range of high-affinity receptors on cells in the arterial wall, such as endothelial cells, macrophages, and smooth muscle cells, which are key players in ...

Oxidized cholesterols (oxycholesterols) in food have been recognized as strong atherogenic components, but their tissue distributions and roles in cardiovascular diseases remain unclear. To investigate whether accumulation of oxycholesterols is linked to cardiac morphology and function, and whether reduction of oxycholesterols can improve cardiac performance, domestic male swine were randomized...

ABSTRACT L-carnitine perform a major role in transporting long-chain fatty acids into the mitochondria, where they are oxidized. It has been used animal diets to decrease fat and increase muscle protein. The aim of this study was evaluate zootechnical performance, degree steatosis liver, genotoxic potential Astyanax lacustris fed with different levels (LC). Yellowtail tetra juveniles (n = 140) ...

introduction: inappropriate body composition represents impaired energy and nutrient intake and can be a risk factor for many diseases, especially for cardiovascular disease. different methods have been suggested for the estimation of body fat volume and its distribution. however, they may be either expensive or hazardous for some groups of patients. sonography is a very accessible technique, w...

In the first paper of this series (Lea, Parr & Carpenter, 1958) we reported the results of experiments on the effect of storage on the nutritive value of herring meal as a source of protein for chicks. Over a period of 24 months’ storage in air there was extensive oxidation of the lipids, but only a very small drop in ‘available’ lysine (lysine with a chemically reactive E-NH, group) and no sig...