Blood lipid levels, including low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG), are highly heritable traits and major risk factors for atherosclerotic cardiovascular disease (CVD). Using individual ancestry estimates at marker locations across the genome, we present a novel quantitative admixture mapping analysis of all three lipid...

It is generally assumed that skin vascular resistance contributes only to a small extent to total peripheral resistance and hence to blood pressure (BP). However, little is known about the impact of skin blood flow (SBF) changes on the diurnal variations of BP under ambulatory conditions. The main aim of the study was to determine whether diurnal patterns of distal SBF are related to mean arter...

Abstract Gravitational lenses can magnify distant galaxies, allowing us to discover and characterize the stellar populations of intrinsically faint, quiescent galaxies that are otherwise extremely difficult directly observe at high redshift from ground-based telescopes. Here, we present spectral analysis two lensed, z ≳ 1 discovered by ASTRO 3D Galaxy Evolution with Lenses survey: AGEL 1323 ( M...

Background: In the clinical evaluation of patients with Guillain–Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), scant attention is paid to symptoms such as fatigue, pain and anxiety/depression. We aimed at addressing seminal studies that focused on the burden of these symptoms and their impact on quality of life (QoL) in these conditions. Summary: Fat...

Background: Anti-neutrophil cytoplasmic antibody (ANCA)associated vasculitis (AAV) comprises microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA) and eosinophilic GPA (EGPA). Myeloperoxidase (MPO) and proteinase 3 (PR3) are the main antigens for ANCA. AAV is a common multisystem autoimmune disease and most of the studies on AAV have been conducted in Western countries. Nowaday...

microorganisms are important components of soil. some soil filamentous fungi such aspenicilium produce many bioactive small molecules, or secondary metabolites, that range frombeneficial bioactive compounds to harmful toxins. in this study, the metabolites of threepenicillium species (p. goditanum, p. moldavicum and p. corylophilum) were extracted byadding ethyl acetate to liquid cultures. the ...

let $g$ be a finite $p$-soluble group‎, ‎and $p$ a sylow $p$-subgroup of $g$‎. ‎it is proved‎ ‎that if all elements of $p$ of order $p$ (or of order ${}leq 4$ for $p=2$) are‎ ‎contained in the $k$-th term of the upper central series of $p$‎, ‎then the $p$-length of‎ ‎$g$ is at most $2m+1$‎, ‎where $m$ is the greatest integer such that‎ ‎$p^m-p^{m-1}leq k$‎, ‎and the exponent of the image of $p$...

for a symmetric group $g:=sym(n)$ and a conjugacy class $mathcal{x}$ of involutions in $g$, it is known that if the class of involutions does not have a unique fixed point, then - with a few small exceptions - given two elements $a,x in mathcal{x}$, either $angbrac{a,x}$ is isomorphic to the dihedral group $d_{8}$, or there is a further element $y in mathcal{x}$ such that $angbrac{a,y} cong ang...