13C metabolic flux analysis (MFA) is a tool of metabolic engineering for investigation of in vivo flux distribution. A direct 13C enrichment analysis of intracellular free amino acids (FAAs) is expected to reduce time for labeling experiments of the MFA. Measurable FAAs should, however, vary among the MFA experiments since the pool sizes of intracellular free metabolites depend on cellular meta...

. TRESOR hat den Aufbau eines sicheren und datenschutzkonformen Cloud-Ecosystems zum Ziel, welches exemplarisch für den Anwendungsbereich der Patientenversorgung im Gesundheitswesen umgesetzt wird. 1. Über Trusted Cloud Das Forschungsprojekt TRESOR der Konsortialpartner medisite Systemhaus GmbH, TSystems International GmbH, Ubiry GmbH, TU Berlin Service-centric Networking, TU Berlin Wirtschaft ...

Cloud computing combination of hardware and software resources made available on the Internet as managed third-party services. These services typically provide access to advanced software applications and highend networks of server computers. Cloud computing is a general term for anything that involves delivering hosted services over the Internet. These services are broadly divided into three c...

The Cloud computing market encompasses an ever-growing number of providers offering a multitude of infrastructure-as-a-service (IaaS) and platform-as-a-service (PaaS) solutions. In order to exploit the peculiarities of each Cloud solution as well as to optimize performances, availability, and cost, an emergent need is to run and manage multi-Cloud applications [1] (i.e., applications that can e...

Background: Changing emotional and physical status along with increasing social, family and academic pressure lead to various impairments in mental health of adolescents. Objective: To examine the level of stress and its consequences in school going adolescences and examine adolescent’s adjustment at various placeshome, school, peers, teachers and general matters. Methods: A descriptive and a s...

BACKGROUND Over the past decades, attachment research has predominantly focused on the attachment relationship that infants develop with their parents or that adults had with their own parents. Far less is known about the development of feelings of attachment in parents towards their children. The present study examined a) whether a simple non-verbal (i.e., pictorial) measure of attachment (Pic...

We consider a three-tiered cloud service market and propose an energy efficient pricing strategy in this market. Here, the end customers are served by the Software-as-a-Service (SaaS) providers, who implement customized services for their customers. To host these services, these SaaS providers, in turn, lease the infrastructure related resources from the Infrastructure-as-a-Service (IaaS) or Pl...

Platform-as-a-Service (PaaS) clouds free companies of building infrastructures dimensioned for peak service demand and allow them to only pay for the resources they actually use. Being a PaaS cloud customer, on the one hand, o↵ers a company the opportunity to provide applications in a dynamically scalable way. On the other hand, this scalability may lead to financial loss due to costly use of v...

L-type calcium channels (Cav1.m) inactivate in response to elevation of intracellular Ca 21 (Ca-dependent inactivation) and additionally by conformational changes induced by membrane depolarization (fast and slow voltage-dependent inactivation). Molecular determinants of inactivation play an essential role in channel inhibition by phenylalkylamines (PAAs). The relative impacts, however, of Ca-d...

ion allowing access to infrastructure resources (e.g. storage, computation, server, data center) on-demand and paid according to the required quality-of-service (QoS). • Platform layer: Known as Platform as a Service (PaaS) extends the IaaS layer by hiding the IaaS complexity. PaaS is accessed as one big system and not by accessing individual virtual machines. Therefore, it provides an abstract...