The p21-activated kinases (Paks) are serine/threonine kinases that are major effectors of the Rho guanosine 5'\x{2011}triphosphatase, Rac, and Cdc42. Rac and Cdc42 are known regulators of hematopoietic stem and progenitor cell (HSPC) function, however, a direct role for Paks in HSPCs has yet to be elucidated. Lin(-)Sca1(+)c-kit(+) (LSK) cells from wild-type mice were transduced with retrovirus ...

Rac1 is a member of the Rho family of GTPases, which includes Rho, Rac, and cdc42 subfamilies.1,2 On activation by guanine nucleotide exchange factors, the Rho family GTPases exchange a GDP molecule for a GTP and act as molecular switches to transduce signals in response to various extracellular stimuli.2 Apart from their characteristic role in the regulation of cytoskeletal rearrangement and c...

Teh ultrasound-assisted magnetic stirrer was used as an effective extraction technique for teh evaluation of total phenolic contents (TPC) and antioxidant potential of ten Pakistani brown rice cultivars. For this purpose, ultrasonic (240W frequency 50/60 Hertz) assisted magnetic stirrer coupled with three solvents methanol, ethanol, and isopropanol in pure and aqueous fractions (80:20) were...

The following manuscript has been retracted from our November – December, 2016 issue. It has been retracted on a request from the authors as they forgot to properly acknowledge the source of their data. The authors are grateful to those who pointed out this mistake. Editor Retraction in: Pak J Med Sci 2016;32(6):1500-1505. doi: https://doi.org/10.12669/pjms.326.11460 Link: http://pjms.com.pk/in...

Kronecker coefficients encode the tensor products of complex irreducible representations of symmetric groups. Their stability properties have been considered recently by several authors (Vallejo, Pak and Panova, Stembridge). In [3] we described a geometric method, based on Schur-Weyl duality, that allows to produce huge series of instances of this phenomenon. In this note we show how to go beyo...

Context of our work. Describing typical properties of permutations in a given class is a question that has received quite a lot of attention in the last few years. Most of the attention is focused on permutation classes Av(τ) for τ of size 3. See for instance the very precise description of the asymptotic shape of permutations in these classes by Miner and Pak [12], or the link between large ra...

Pak-Wing Fok,1 Rodolfo R. Rosales,2 and Dionisios Margetis3 1Applied and Computational Mathematics, California Institute of Technology, Pasadena, California 91125, USA 2Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA 3Department of Mathematics and Institute for Physical Science and Technology, University of Maryland, College Park, Maryland 2...

It is known that the Pak-Stanley labeling of the Shi hyperplane arrangement provides a bijection between the regions of the arrangement and parking functions. For any graph G, we define the G-semiorder arrangement and show that the Pak-Stanley labeling of its regions produces all G-parking functions. In his study of Kazhdan-Lusztig cells of the affine Weyl group of typeAn−1, [10], J.-Y. Shi int...