O movimento de popularização das Plantas Alimentícias Não Convencionais (PANC) no Brasil tem avançado sentido ampliar a disponibilidade desses alimentos nos mercados locais, principalmente nas feiras. presente trabalho teve como objetivo analisar oferta PANC entre os(as) agricultores(as) agroecológicos(as) da feira São Lourenço do Sul, RS, e avaliar as transformações ocorridas partir iniciativa...

Many cancers develop different means of escaping destruction by the immune system, such as resistance to Fas ligand (FasL)-Fas interaction-mediated apoptotic signals. Decoy receptor 3 (DcR3), a soluble receptor for FasL, is highly expressed in cancer cells and plays a significant role in immune suppression and tumor progression. However, how DcR3 expression is modulated is unclear. In this stud...

Type B gelatin-based engineered nanovectors system (GENS) was developed for systemic gene delivery in the treatment of pancreatic cancer. The surface of thiolated gelatin nanoparticles was modified with epidermal growth factor receptor (EGFR) specific peptide that targets on the EGFR receptor of Panc-1 cells and this system could release the payload under reducing environment, such as high intr...

We used flow cytometry and a DNA-binding dye efflux assay to isolate a side population (SP) of cells with stem cell characteristics from the human pancreatic carcinoma cell line, PANC-1. Non-obese diabetic/severe combined immunodeficiency mouse xenograft experiments showed that SP cells were enriched in tumor initiating capability compared with non-SP cells. Cultured SP cells were able to diffe...

The FRAP-p70s6K signaling pathway was found to be constitutively phosphorylated/active in MiaPaCa-2 and Panc-1 human pancreatic cancer cells and a pancreatic cancer tissue sample as judged by the retarded electrophoretic mobility of the two major FRAP downstream targets, p70s6K and 4E-BP1. Treatment of cells with rapamycin, a selective FRAP Inhibitor, inhibited basal p70s6K kinase activity and ...