primary pancreatic leiomyosarcomas are rare malignant neoplasms with an aggressive course and a large size. a 56-year-old woman presented with an 8-year history of abdominal pain. multislice computed tomography revealed a large heterogeneous mass with necrotic, calcified and macroscopic fatty areas. the tumor was excised. histopathological evaluation revealed leiomyosarcoma of the pancreas. if ...

introduction: management of early relapsed or refractory lymphoma [hodgkin & non- hodgkin lymphoma (hl & nhl)] is a matter of problem, especially when hematopietic stem cell support is not available. the aim of this study was to evaluate effectiveness of iev regimen ( ifosfamide, epirubicin, vp16), in lymphoma patients who are not candidate for stem cell transplantation. because the majority of...

compared to western countries, pancreatic cancer has a relatively low incidence in iran. it is rarely diagnosed before the fifth decade in iran and most of the patients are older than 60 at the time of diagnosis like to the western countries, where pancreatic cancer is a disease of advanced age. the incidence of the disease in some young patients suggests a possible role of genetic defects, whi...

background: more than 250,000 people die annually of pancreatic cancer, worldwide. the highest incidence and mortality rates of pancreatic cancer are reported in developed countries. in developing countries the rate have been stabilizing over the past two decades but in countries which rates have been low for decades is now increasing. recognizing pancreatic cancer's risk factors and its preven...

in pancreatic survey, quantitative and morphological characteristics could be fundamental variables for the evaluation of some structures. the aim of this study was the application of stereological methods for estimation of quantitative parameters and morphological evaluation of the pancreas in chickens. ten adult male and ten adult female native chickens were used in this study. routine tissue...

the aim of the present study was to investigate the effect of gender on the distribution of pancreatic islets in native chicken. ten adult male and ten adult female isfahan native chickens were used in this experiment. results showed a distinct sexual dimorphism in the native chicken pancreas which depends upon the various fractions of the pancreatic lobes, which were occupied by alpha, beta an...

Methods From February 2008 to April 2014 we have treated 148 malignant cases. Of those, 48 cases of non resectable pancreatic tumors were treated from March 2010 to April 2014, and we include the first 43 patients to the analysis (until December 2013). All of them underwent systemic chemotherapy with a standard combination. Clinical responses (thermical ablation achieved) were measured by image...

Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is a member of the nuclear receptor superfamily and a ligand-activated transcription factor that is involved in the regulation of the inflammatory response via activation of anti-inflammatory target genes and ligand-induced disassociation with the transcriptional repressor B-cell lymphoma 6 (BCL6). Chronic pancreatitis is considered to be...

Non-Hodgkin lymphoma is very uncommon in infancy and skin as the primary site of involvement in Non-Hodgkin lymphoma is rarely encountered. We describe a 10-month-old infant with T-cell Non-Hodgkin lymphoma who presented with multiple skin nodules as the predominant feature of her disease. The clinical manifestations, treatment strategy and disease outcome are reviewed. Key words: Non-Hodgk...

Pancreatic cancer is an aggressive disease with a particularly poor prognosis contributing to a substantial percentage of cancer-associated mortality rates. In the present study, the combination treatment of baicalein (BAI) and gemcitabine (GEM) was investigated to examine whether it inhibited the growth of the human CFPAC-1 pancreatic cancer cell line in vitro and in vivo. The cytotoxic intera...