نتایج جستجو برای: papillon lefevre syndrome

تعداد نتایج: 624241  

2007
Cristian Preda Gilbert Saporta G. Saporta

Clusterwise regression is applied to functional data, using PCR and PLS as regularization methods for the functional linear regression model. We compare these two approaches on simulated data as well as on stock-exchange data.

2007
Ian Rutherfurd

Many of the conclusions in this chapter can be summarised in an acronym that can be remembered by the phrase " Please Think " — PLS –T. 1. PROCESS — Managers will be most effective in targeting riparian revegetation if they first understand the erosion mechanisms (the processes) that are acting in a particular stream or river reach. 2. LEVERAGE — Once we understand the erosion mechanism, then w...

Journal: :Journal of immunology 2004
Christine T N Pham Jennifer L Ivanovich Sofia Z Raptis Barbara Zehnbauer Timothy J Ley

A variety of neutral serine proteases are important for the effector functions of immune cells. The neutrophil-derived serine proteases cathepsin G and neutrophil elastase are implicated in the host defense against invading bacterial and fungal pathogens. Likewise, the cytotoxic lymphocyte and NK cell granule-associated granzymes A and B are important for the elimination of virus-infected cells...

Journal: :Journal of North Khorasan University of Medical Sciences 2011

Journal: :JEADV Clinical Practice 2023

Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disease that presents clinically with palmoplantar keratoderma and periodontitis results in early-onset dental loss. PLS management difficult. We report 30-year-old female who had unfavourable response to topical keratolytic creams, oral isotretinoin narrow-band ultraviolet-B (NB-UVB) phototherapy but showed significant clinical impr...

2015
Basapogu Sreeramulu Naragani DVN Shyam Pilla Ajay Pathipaka Suman

Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder, characterized by diffuse palmoplantar keratoderma and precocious aggressive periodontitis, leading to premature loss of deciduous and permanent dentition at a very young age. Various etiopathogenic factors are associated with the syndrome, like immunologic alterations, genetic mutations, and the role of bacteria. Dentists p...

Journal: :Journal of medical genetics 2000
P S Hart Y Zhang E Firatli C Uygur M Lotfazar M D Michalec J J Marks X Lu B J Coates W K Seow R Marshall D Williams J B Reed J T Wright T C Hart

INTRODUCTION Papillon-Lefèvre syndrome (PLS) is an autosomal recessive disorder characterised by palmoplantar keratoderma and severe, early onset periodontitis, which results from deficiency of cathepsin C activity secondary to mutations in the cathepsin C gene. To date, 13 different cathepsin C mutations have been reported in PLS patients, all of which are homozygous for a given mutation, refl...

Journal: :مجله دانشکده دندانپزشکی مشهد 0
مریم مریم شریفی maryam sharifi assistant professor, dept of pediatric dentistry, school of dentistry rafsanjan university of medical sciences, rafsanjan, iran.استادیار گروه دندانپزشکی کودکان، دانشکده دندانپزشکی، دانشگاه علوم پزشکی رفسنجان، رفسنجان، ایران سمیه سمیه خرمیان طوسی somayeh khoramian tusi assistant professor, dept of pediatric dentistry, school of dentistry, alborz university of medical sciences, karaj, iran.استادیار گروه دندانپزشکی کودکان، دانشکده دندانپزشکی، دانشگاه علوم پزشکی البرز، کرج، ایرانسازمان اصلی تایید شده: دانشگاه علوم پزشکی رفسنجان (rafsanjan university of medical sciences)

مقدمه: سندرم papillon-lefevre یک بیماری نادر اتوزومال مغلوب است. این بیماری با هایپرکراتوز کف دست و پا و پریودنتیت سریع پیشرونده مشخص می شود و منجر به از دست رفتن پیش از موعد دندان های شیری و دائمی می گردد. تشخیص و درمان به موقع می تواند مانع از درگیری دندان های دایمی و بهبود پریودنتال و ماندگاری بیشتر دندان های شیری گردد و در پیشگیری از تحلیل ریج استخوانی زودهنگام و ایجاد مشکلات پروتزی برای بی...

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