OBJECTIVE This study was aimed to analyze the scavenging effect of haemoperfusion on plasma paraquat (PQ) and to evaluate the clinical significance of PQ examination in the treatment of patients with acute paraquat poisoning. METHODS 85 patients with acute paraquat intoxication by oral ingestion were admitted in West China Hospital from Jun, 2010 to Mar, 2011. A standardized therapeutic regim...

rapeseed is the most widely used oil crop in europe and it is an ideal raw material for the production of biodiesel. because of a high nutritional value and a relatively high omega-3 fatty acids content, rapeseed cake can be used in poultry nutrition for the enrichment of meat and eggs. therefore, the aim of this study was to determine the possibility of using rapeseed cake in diets for turkeys...

Paraquat is a contact and non-selective herbicide which is used for controlling a wide range of terrestrial weeds and aquatic plants. A long-term contact with this xenobiotic can potentially lead to injuries in fishes as live non-target organisms. Therefore, the current study aimed to investigate the effect of sub-lethal toxicity of paraquat on the pathology of gill, liver, and spleen tissues i...

A boronium-based paraquat analog undergoes reductions at more negative potentials than paraquat itself, making it a promising building block for electroactive materials.

A rapid and sensitive method for the analysis of paraquat and diquat was developed using LC/MS, electrospray ionisation (ESI), positive ion mode, selective ion monitoring (SIM) large volume injections, and minimal sample preparation. No trace enrichment was required to obtain limits of detection (LOD) below 1 μg/L, which is well below the World Health Organisation (WHO) advisory value of 10 μg/...

The acute respiratory distress syndrome (ARDS) is an important and common medical emergency. This study aimed to explore the molecular mechanism on how paraquat induced the occurrence of acute respiratory distress syndrome (ARDS). Rats were selected and treated with saline and paraquat for 5 and 21 days, respectively. Lung tissues were selected. Quantitative RT-PCR and western blotting were per...

Paraquat, MPTP, and rotenone reproduce features of Parkinson's disease (PD) in experimental animals. The exact mechanisms by which these compounds damage the dopamine system are not firmly established, but selective damage to dopamine neurons and inhibition of complex I are thought to be involved. We and others have previously documented that the toxic metabolite of MPTP, MPP+, is transported i...

This work presents the first development of an all-steps-in-one test kit for determination paraquat in natural water, and vegetable agricultural samples. A handheld photometer incorporated with a magnetic stirrer was used to complete steps extraction, mixing, detection. Paraquat produces blue free radical ion via reduction sodium dithionite alkaline conditions. Sodium powder investigated enhanc...

Hyperoxia and paraquat ingestion are two clinical examples of lung injury thought to be mediated by oxidant mechanisms. An in vitro cytotoxicity assay using freshly explanted 51Cr-labeled lung tissue as the target was used to quantify the ability of hyperoxia and paraquat to directly injure lung parenchymal cells in an environment where indirect mechanisms such as recruitment of inflammatory ce...

Breeding of yellow-seeded rapeseed (Brassica napus) is preferred over black-seeded rapeseed for the desirable properties of the former. This study evaluated the metabolites and nutritive values of black-seeded rapeseed meal and yellow-seeded meal from the progeny of a B. napus-Sinapis alba hybrid. Yellow-seed meal presented higher protein (35.46% vs. 30.29%), higher sucrose (7.85% vs. 7.29%), l...