The present study was conducted on 120dogs at the Teaching Veterinary Clinical Complex (TVCC), C.V.Sc. and A.H., OUAT, Bhubaneswar showing the symptoms of haemorrhagic gastro enteritis were made against CPV infection to reveal the haematological, serum biochemical alterations and efficacy of different therapeutic regimens. Significant variations were found in both hematological and sero-biochem...

The parotid is the salivary gland most affected by inflammatory process. The authors reviewed the records of 36 patients with acute suppurative parotitis admitted between July 1996 and June 2002. All patients had unilateral swelling of the cheek that extended to the angle of the jaw; 23 had fever (64%) and 6 diabetes (17%). Even though Staphylococcus aureus is the usual pathogen in acute suppur...

Toxic epidermal Necrolysis (TEN) are serious disorders commonly termed as idiosyncratic reactions to drug, the most common being antiepileptic(phenytoin, barbiturates, carbamazepine and lamotrigine), sulfonamides, trimethoprim, ampicillin, allopurinol and NSAIDS (especially phenylbutazone and oxicam derivatives). Here we report a case of TEN in a patient who developed the lesion after oral admi...

loon dilation is 0-14% (1-3). An esophageal perforation is classified into three types: a type I-intramural perforation; a type II-transmural perforation; and a type IIItransmural perforation with mediastinal leakage (4). Fasting, parenteral alimentation, and antibiotics are generally used to treat types-I and II esophageal perforations. However, a type III esophageal perforation showing progre...

BACKGROUND Nearly half of all hospitalized infants with respiratory syncytial virus (RSV) lower respiratory tract disease (LRTD) are treated with (parenteral) antibiotics. The present study was designed to test our hypothesis that the use of antibiotics would not lead to a reduced duration of hospitalization in mild to moderate RSV LRTD. METHODS Seventy-one patients < or =24 months of age wit...

This study compared adverse drug reactions (ADRs) to oxacillin with those to nafcillin and other antibiotics. We reviewed the medical records of 222 children receiving outpatient parenteral antimicrobial therapy (OPAT) from February 1995 through June 1999. The diagnosis, antibiotics used, ADRs, action taken, and patient demographics were recorded. The most common ADRs were neutropenia (9.8%), r...

The increase in serious gram-positive infections has increased the need for treatment of gram-positive infections in patients with hematologic malignancies. Common gram-positive pathogens exhibit a variety of resistance mechanisms, and this has supported the need for new antibiotics with unique modes of action and no endogenous resistance mechanism(s) directed against them. Linezolid (Zyvox), t...

OBJECTIVE To compare the efficacy of oral antibiotic treatment alone with treatment started parenterally and completed orally in children with a first episode of acute pyelonephritis. DESIGN Multicentre, randomised controlled, open labelled, parallel group, non-inferiority trial. SETTING 28 paediatric units in north east Italy. PARTICIPANTS 502 children aged 1 month to <7 years with clini...

OBJECTIVE There is a global call for formulations, which are better suited for children of different age categories and in a variety of settings. One key public health area of interest is age-appropriate paediatric antibiotics. We aimed to identify clinically relevant paediatric formulations of antibiotics listed on pertinent formularies that were not on the WHO Essential Medicines List for Chi...

Certain antibiotics, particularly piperacillin, have been reported to be associated with a high incidence of allergic reactions in patients with cystic fibrosis. We initiated a study to determine the relative frequency of allergic reactions, ie, drug-induced fever and rash, to parenteral beta-lactam antibiotics in adult patients with cystic fibrosis. Charts of 111 patients were reviewed for eac...