OBJECTIVE
To assess the response to the rotigotine transdermal system (Neupro; Schwarz Pharma Ltd, Monheim, Germany), a nonergolinic dopamine agonist, in patients with early Parkinson disease.
DESIGN
Randomized, double-blind, multicenter, placebo-controlled study.
SETTING
Fifty sites in the United States and Canada.
PATIENTS
Two hundred seventy-seven patients with early Parkinson disease....
