Low-pH- and calcium-induced aggregation of regulated secretory proteins has been proposed to play a role in their retention and storage in secretory granules. However, this has not been tested for secretory proteins that are stored in the exocrine parotid secretory granules. Parotid granule matrix proteins were analyzed for aggregation in the presence or absence of calcium and in the pH range o...

PURPOSE To revisit and reintroduce sialography as an important tool for the assessment and diagnosis of salivary gland obstruction. PATIENTS AND METHODS A sample of 30 consecutive patients undergoing sialography was selected. Parotid sialography was performed in 22 patients (12 females and 10 males). The patients undergoing parotid sialography presented with bilateral or unilateral enlargemen...

The distribution of amylase in rat parotid glands and von Ebner's glands was examined using ion etching-immunoscanning electron microscopy, which enables both light and electron microscopic observations of identical semi-thin resin sections immunolabeled with anti-α-amylase and immunogold in association with silver enhancement. At the light microscopic level, most acinar secretory granules (SG)...

INTRODUCTION The most common cause of parotid fistula is trauma, followed by malignancy, operative complications (parotidectomy or rhytidectomy) and infection. Acute suppurative parotitis can rarely produce parotid fistula. There are various treatment options available, however it is necessary to standardize the treatment according to the duration of history and the patient's general condition....

OBJECTIVES To define (1) at-risk structures during the orthodromic temporalis tendon transfer and (2) achievable tendon length without temporal releasing incisions or perioral lengthening materials. METHODS Ten fresh cadavers provided 20 hemifaces for dissection. Measurements and photographic documentation were used to examine the parotid duct, masseteric artery, inferior alveolar nerve, inte...

BACKGROUND Surgery for benign parotid tumors has undergone several evolutionary steps over the past century. Prior to the 1930s, the focus of parotid surgery was to limit the risk of facial nerve paralysis, which made intracapsular enucleation the most common procedure performed. However, it became widely recognized that the postoperative risk of recurrence was unacceptably high, even for benig...

Objective Fine-needle aspiration cytology is a valuable method for preoperative assessment of head and neck tumors. However, its accuracy in detection of salivary gland masses is controversial compared with other methods. The aim of this work was to evaluate the effectiveness and accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of parotid gland masses. Material and Methods ...

BACKGROUND Carcinoma ex pleomorphic adenoma (CXPA) of the parotid gland is a high-grade cancer and the prognosis of this cancer has not been compared with non-CXPA high-grade primary parotid cancer. METHODS Retrospective medical chart review of patients with surgically treated high-grade primary parotid cancer (21 CXPA and 52 non-CXPA) was performed with correlation with disease-specific surv...

OBJECTIVES/HYPOTHESIS Parotid gland calcifications can be incidental findings on computed tomography (CT) and have been reported to be associated with chronic inflammatory conditions. Associations between parotid gland calcification and other common medical conditions have not been reported. METHODS Following institutional review board approval, 1,571 patients who underwent noncontrast head C...

BACKGROUND: Among salivary gland tumors, 80% arise in the parotid glands. Parotid tumors pose a challenge to most surgeons both in diagnosis and treatment. This study evaluates the clinical profile and management outcomes of parotid gland tumors in Port Harcourt, Nigeria. MATERIALS AND METHODS: The records of patients who presented with parotid gland swellings to the department of Ear, Nose and...