Abstract Introduction The atypical antipsychotic quetiapine is known to induce weight gain and other metabolic complications. underlying mechanisms are multifactorial poorly understood with almost no information on the effect of dosage. Concerns were thus raised rise in low-dose off-label prescription (i. e.,<150 mg/day). Methods In this study, we evaluated influence dose for 474 patients in...

OBJECTIVE This analysis was conducted to determine the likelihood of identifying an effective dose of fentanyl sublingual tablet during the initial titration phase of 2 clinical trials, to characterize the actual effective dose in patients achieving successful titration, and to examine the relationship between baseline characteristics and likelihood of achieving an effective dose. METHODS Dat...

background: in radiation therapy, the peripheral dose is important when anatomical structures with very low dose tolerances are involved. in this study, the two available calculation algorithms of the varian eclipse 8.6 treatment planning system(tps), the anisotropic analytic algorithm (aaa) and pencil-beam convolution (pbc) was used to compare measured and calculated peripheral dose distributi...

Introduction: Metal prostheses in patients affect the radiotherapy dose distribution. Metal prostheses with high density and atomic number cause major changes in scattering and attenuation of radiation. The present study aims to assess the impact of metal knee prosthesis with various dimensions and materials on radiotherapy dose distribution. Material and Methods: In this research, the Varian L...

 ABSTRACT Background: Aspirin even at low dose ( 100 mg) can increase the risk of upper gastrointestinal bleeding. It is usual to use low dose aspirin for cardiovascular prophylaxis. We hypothesized that Helicobacter pylori eradication is as effective as omeprazole maintenance therapy for secondary prevention of bleeding in those who take low dose aspirin and are positive for Helicobacter pylor...