Although the oligometastatic type of prostate cancer (PCa) is subject much research, it still has no clear biological and clinical specification. It a condition between localized extensive PCa, in which early diagnosis treatment are favorable prognostic factors. Not so long ago, just presence metastases was considered poor prognosis with limited therapeutic options. Such patients were treated a...

BACKGROUND Prostate cancer (PCa) and benign prostatic hyperplasia (BPH) are diseases of elderly men and are related to increased oxidative stress (OS). Although prolidase has a role in collagen metabolism, it is also used to evaluate OS in many diseases. However, there is a lack of data about serum prolidase activity (SPA) in prostate cancer. The aim of this study was to evaluate and compare SP...

Posterior cortical atrophy (PCA) is a neurodegenerative syndrome characterized by predominant visual deficits and parieto-occipital atrophy, and is typically associated with Alzheimer's disease (AD) pathology. In AD, assessment of hippocampal atrophy is widely used in diagnosis, research, and clinical trials; its utility in PCA remains unclear. Given the posterior emphasis of PCA, we hypothesiz...

OBJECTIVES Emerging evidence indicates that prostatic inflammation may contribute to prostate growth either in terms of hyperplastic (benign prostatic hyperplasia [BPH]) or neoplastic (prostate cancer [PCa]) changes. We propose two questions: Does prostate inflammation represent a significant factor for the development and the progression of both BPH and PCa? Are data available now to sustain t...

BACKGROUND The thorough assessment of familial prostate cancer (PCa) risk is as important as ever to provide a basis for clinical counselling and screening recommendations. OBJECTIVE Our aim was to determine the age-specific risks of PCa and the risk of death from PCa according to the number and the age of affected first-degree relatives. DESIGN, SETTING, AND PARTICIPANTS The nationwide Swe...

New markers based on PSA isoforms have recently been developed to improve prostate cancer (PCa) diagnosis. However, novel approaches are still required to differentiate aggressive from non-aggressive PCa to improve decision making for patients. PSA glycoforms have been shown to be differentially expressed in PCa. In particular, changes in the extent of core fucosylation and sialylation of PSA N...

There are inconsistent findings concerning the association between serum concentrations of lipid parameters and prostate cancer (PCa), particularly in Caucasian men. is limited data on men African ancestry. The study examined relationship total cholesterol (TC) levels its fractions PCa a hospital-based case-control Jamaica. TC, triglycerides (TG), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C...

Purpose: The diagnosis of pediatric autoimmune gastritis (AIG) is critical due to the poor outcome and risk malignancy. Therefore, we evaluated prevalence in children with thyroid disease (ATD) type 1 diabetes mellitus (T1D), using parietal cell antibody (PCA) identify its use as a screening test. Methods: PCA was measured 90 patients; 45 patients ATD (Hashimoto Thyroiditis Graves' Disease) T1D...

Logistic regression is a simple statistical tool used in binary classification. LR is useful for situations in which we want to predict the presence or absence of a characteristic or outcome based on values of a set of predictor variables. Unlike LR, PCA is another technique used in feature extraction and in dimensionality reduction. This paper puts forth the experimental results of LR model an...