in this paper, a high speed delay-locked loop (dll) architecture ispresented which can be employed in high frequency applications. in order to design the new architecture, a new mixed structure is presented for phase detector (pd) and charge pump (cp) which canbe triggered by double edges of the input signals. in addition, the blind zone is removed due to the elimination of reset signal. theref...

this paper presents h∞ control problem for input-delayed systems. a neutral system approach is considered to the design of pd controller for input delay systems in presence of uncertain time-invariant delay. using this approach, the resulting closed-loop system turns into a specific time-delay system of neutral type. the significant specification of this neutral system is that its delayed coeff...

New reliable biomarkers are needed to predict the response to immune checkpoint inhibitors against programmed death-1 (PD-1) and its ligand (PD-L1), because PD-L1 expression on tumor cells has limited power for selecting patients who may benefit from such therapy. Here we investigated the significance of PD-L1 and PD-L2 gene copy number gains using fluorescence in situ hybridization as well as ...

Objective. The main aim of this study was to verify the sensitivity and specificity of Addenbrooke's Cognitive Examination-Revised (ACE-R) in discriminating between Parkinson's disease (PD) with normal cognition (PD-NC) and PD with mild cognitive impairment (PD-MCI) and between PD-MCI and PD with dementia (PD-D). We also evaluated how ACE-R correlates with neuropsychological cognitive tests in ...

PD-1-PD-L1 interaction is known to drive T cell dysfunction, which can be blocked by anti-PD-1/PD-L1 antibodies. However, studies have also shown that the function of the PD-1-PD-L1 axis is affected by the complex immunologic regulation network, and some CD8+ T cells can enter an irreversible dysfunctional state that cannot be rescued by PD-1/PD-L1 blockade. In most advanced cancers, except Hod...

Presenter: Daisy Sanchez MD | Memorial Healthcare System Background: Current literature presents limited data regarding outcomes following conversion at the time of minimally invasive pancreaticoduodenectomy (MI-PD). We aim to compare perioperative, oncologic and survival between patients who required from MI-PD open (CO-PD) with underwent pancreatectomy (O-PD) on a national level. Methods: The...

Thermal treatment of the Pd complex bearing triphenylphosphine (PPh3) and acetate as ligands (bis(triphenylphosphine)palladium(II) diacetate, Pd(PPh3)2(OAc)2) in toluene resulted formation aggregated nanoparticles (Pd-NPs). The dispersion could be achieved after addition *BEA zeolite during thermal Pd(PPh3)2(OAc)2 (Pd/*BEA). Further, Suzuki cross-coupling was performed on prepared catalysts uti...

The performances of different promoters (CeO2, ZrO2 and Ce0.5Zr0.5O2 solid solution) modified Pd/SiC catalysts for methane combustion are studied. XRD and XPS results showed that Zr 4+ could be incorporated into the CeO2 lattice to form Zr0.5Ce0.5O2 solid solution. The catalytic activities of Pd/CeO2/SiC and Pd/ZrO2/SiC are lower than that of Pd/Zr0.5Ce0.5O2/SiC. The Pd/Zr0.5Ce0.5O2/SiC catalys...