The thoracic cavity is the rarest location of all the renal ectopic sites. We report a rare case of an acquired thoracic kidney associated with a previous congenital diaphragmatic hernia in a child with nephrotic syndrome. Although only 13 cases of the thoracic kidney in the pediatric age group have been described in worldwide reports during the past 25 years, we present the first to be associa...

We describe a case of a 55-year-old man who presented with pulmonary embolism and who was found to have nephrotic syndrome due to idiopathic membranous nephropathy. There are no other signs of nephrotic syndrome such as edema.

CNS (Congenital nephrotic syndrome) is a disorder characterized by the presence of a nephrotic syndrome in the first three months of life. Different pathologies can cause this syndrome. In general, we can distinguish primary forms (sporadic and hereditary) and secondary forms (acquired and associated with other syndromes). The most common form is the Finnish CNS (CNF, congenital nephrotic syndr...

Three sibs born to consanguineous parents had congenital nephrotic syndrome, microcephaly, and psychomotor retardation. Pathology of the kidneys showed diffuse mesangial sclerosis with deposits of IgG and C3 in the mesangium and glomerular basement membranes. All three children died before the age of 3 years. Of 19 published cases of children with the association of congenital nephrotic syndrom...

Pneumococcal-associated hemolytic uremic syndrome (pHUS) is a rare but severe complication of invasive Streptococcus pneumoniae infection. We report the case of a 12-year-old female with steroid-resistant nephrotic syndrome treated with adrenocorticotrophic hormone (H.P. Acthar(®) Gel), who developed pneumococcal pneumonia and subsequent pHUS. While nephrotic syndrome is a well-known risk facto...

Adult-onset nephrotic syndrome (NS) differs from its pediatric counterpart in several important ways. Most importantly, NS in adults is more etiologically heterogeneous compared to children, and thus treatment approaches rely heavily on the histological diagnosis provided by renal biopsy. The evidence-based approach to treatment of adult NS has been critically examined by the Kidney Disease Imp...

A 6-year-old previously healthy female from the United States presented with 5 days of high fever to 103F, abdominal pain, and vomiting. Exposure history included recent travel Russia, Turkey, Yosemite, San Diego Zoo, as well multiple mosquito bites. On admission, she was found have thrombocytopenia, hematuria, nephrotic range proteinuria subsequently developed acute kidney injury. Her grandfat...

Glomerulonephritis [GN] is one of the common acquired pediatric renal disorders encountered in clinical practice. The clinical manifestations include gross or microscopic hematuria, proteinuria, and nephrotic syndrome. Renal dysfunction and hypertension may also be present in many patients. Etiopathogenesis of GN can be idiopathic in a large majority, while some may result from infections or kn...

background: the ratio of urine protein to urine osmolality has recently been suggested as an accurate method to determine proteinuria.   objective: we studied the correlation of urine protein to urine osmolality ratio with 24-hr urinary protein excretion.   methods: 150 children aged 0.11–17 years admitted to the department of pediatric nephrology were included in this study. early morning urin...

background osteoporosis is one of the consequences of chronic diseases such as nephrotic syndrome in adolescents, especially in those undergoing glucocorticoid therapies. the present study aimed to determine and compare the effect of education by peers and health personnel on the prevention of osteoporosis in the adolescents with nephrotic syndrome. methods the present quasi-experimental study ...