نتایج جستجو برای: pedunculopontine tegmental nucleus
تعداد نتایج: 114456 فیلتر نتایج به سال:
RATIONALE We report on a patient who showed neural reorganization between injured cingula and the brainstem cholinergic nuclei following cerebral concussion. PATIENT CONCERNS The main concern of the patient is memory impairment. DIAGNOSES Cerebral concussion. OUTCOMES When she visited our hospital at 2 years after onset, cognitive function was evaluated using 2 scales; the Wechsler Intell...
Two patients with Parkinson's disease with pedunculopontine nucleus (PPN) stimulation for gait impairments reported "trembling vision" during the setting of the electrical parameters, although there was no clinically observable abnormal eye movement. Oculomotor recordings revealed frequency locked voltage dependent vertical or oblique movements of the eye ipsilateral to the active contact, sugg...
The pedunculopontine nucleus (PPN) region has received considerable attention in clinical studies as a target for deep brain stimulation (DBS) in Parkinson disease. These studies have yielded variable results with an overall impression of improvement in falls and freezing in many but not all patients treated. We evaluated the available data on the surgical anatomy and terminology of the PPN reg...
Dopamine neurons in the midbrain respond to behavioral events and environmental stimuli. Their different patterns of activation in turn modulate the activity of forebrain regions and modulate the expression of selective behavioral responses. However, their activity is closely dependent on the cholinergic systems in the brainstem. Ascending cholinergic projections from the pedunculopontine and l...
It is believed that depression impedes and motivation enhances functional recovery after neuronal damage such as spinal-cord injury and stroke. However, the neuronal substrate underlying such psychological effects on functional recovery remains unclear. A longitudinal study of brain activation in the non-human primate model of partial spinal-cord injury using positron emission tomography (PET) ...
Serotonin (5-HT) exerts excitatory effects in many brainstem regions involved in autonomic, somatic, motor, and sensory functions, and in control of vigilance. To determine the potential role of 5-HT2A receptors in these effects, we immunohistochemically mapped the distribution of 5-HT2A receptor-like protein in the rat pontomedullary brainstem. Areas containing the densest labeling included th...
The present study determined simultaneously the behavioural, neuroendocrine and regional brain activity, using semi-quantitative analysis of c-fos mRNA induction, produced by 30 min of auditory stimulation at different white noise intensities (background 60 dB, 70, 80, 90 and 105 dBA), in rats. Only the highest noise intensities (90 and 105 dB) significantly increased corticosterone release aft...
BACKGROUND AND PURPOSE Deep brain stimulation (DBS) of the pedunculopontine nucleus (PPN) reduces the number of falls in patients with Parkinson's disease (PD). It was hypothesized that enhanced sensory processing contributes to this PPN-mediated gait improvement. METHODS Four PD patients (and eight matched controls) with implanted bilateral PPN and subthalamic nucleus DBS electrodes were ass...
introduction: the septal region is part of the telencephalon and is a component of the limbic system. the lateral septal area (ls); largest nuclear mass in this region, plays a pivotal role in various physiological processes, such as aggression, emotion, thermoregulation, water and food intake and sexual behaviour. to support the functional analysis of this brain area in the rat, the sources of...
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