نتایج جستجو برای: peg shielded

تعداد نتایج: 19182  

Journal: :Langmuir : the ACS journal of surfaces and colloids 2010
De-Hao Tsai Frank W DelRio Robert I MacCuspie Tae Joon Cho Michael R Zachariah Vincent A Hackley

Competitive adsorption kinetics between thiolated polyethylene glycol (SH-PEG) and mercaptopropionic acid (MPA) on gold nanoparticles (Au-NPs) were studied using a prototype physical characterization approach that combines dynamic light scattering (DLS) and electrospray differential mobility analysis (ES-DMA). The change in hydrodynamic particle size (intensity average) due to the formation of ...

2012
Jong Ho Hwang Hyung Wook Kim Dae Hwan Kang Choel Woong Choi Soo Bum Park Tae Ik Park Woo Sung Jo Dong Hyuk Cha

As a rare complication of percutaneous endoscopic gastroscopy (PEG), a gastrocolocutaneous fistula may occur after PEG placement. This paper reports an interesting case which PEG tube unintentionally penetrated transverse colon during PEG. A 72-year-old female patient who suffered from medullary infarction underwent PEG procedure for enteral nutrition, and fecal materials were observed 6 days a...

Journal: :Bioorganic & medicinal chemistry 2012
Keiichi Motoyama Kayoko Hayashida Taishi Higashi Hidetoshi Arima

Nonviral gene delivery suffers from a number of limitations including short transgene expression times and low transfection efficiency. In this study, we examined whether polypseudorotaxanes (PPRXs) of polyethylene glycol (PEG, molecular weight: 2,000)-grafted α-cyclodextrin (α-CyD)/polyamidoamine dendrimer conjugate (PEG-α-CDE) with CyDs have the potential for the novel sustained release syste...

Journal: :Stroke 2013
Perry H Dubin Amelia K Boehme James E Siegler Amir Shaban Jenifer Juengling Karen C Albright Sheryl Martin-Schild

BACKGROUND AND PURPOSE The need for surgical feeding tube placement after acute stroke can be uncertain and associated with further morbidity. METHODS Retrospective data were recorded and compared across patients with acute ischemic stroke and intracerebral hemorrhage. We identified all feeding tubes placed as percutaneous endoscopic gastrostomy (PEG) tubes. A prediction score for PEG tube pl...

Journal: :Chemical & pharmaceutical bulletin 2008
Xinxin Zhang Weisan Pan Li Gan Chunliu Zhu Yong Gan Shufang Nie

Nanostructured lipid carriers (NLC) are based on mixture of solid lipids with spatially incompatible liquid lipids, which offer advantages of improving drug loading capacity and release properties. In the present study, hydroxycamptothecin (HCPT) loaded polyethylene glycol (PEG) modified NLC (PEG-NLC) was prepared by high pressure homogenize and spray drying method. PEG-NLC showed spherical par...

2016
Mei Zhang You-Kyoung Kim Pengfei Cui Jialiang Zhang Jianbin Qiao Yujing He Jinyuan Lyu Chengqiong Luo Lei Xing Hulin Jiang

Biodegradable polyamines have long been studied as potential recombinant viral gene vectors. Spermine (SPE) is an endogenous tetra-amine with excellent biocompatibility yet poor gene condensation capacity. We have previously synthesized a polyspermine based on SPE and poly(ethylene glycol) (PEG) diacrylate (SPE-alt-PEG) for enhanced transfection performance, but the synthesized SPE-alt-PEG stil...

2014
Jong Pil Im Jae Myung Cha Ji Won Kim Seong-Eun Kim Dong Yup Ryu Eun Young Kim Eun Ran Kim Dong Kyung Chang

BACKGROUND/AIMS Knowledge of the risk factors associated with adverse outcomes after percutaneous endoscopic gastrostomy (PEG) may be helpful for developing PEG recommendations. The purpose of this study was to identify the clinical risk factors associated with adverse clinical outcomes after PEG, especially regarding the use of proton pump inhibitors (PPIs). METHODS We retrospectively review...

Journal: :Biochimica et biophysica acta 1999
K W Mok A M Lam P R Cullis

Previous work has shown that plasmid DNA can be encapsulated in small 'stabilized plasmid-lipid particles' (SPLP) composed of 1, 2-dioleyl-3-phosphatidylethanolamine (DOPE), the cationic lipid N, N-dioleyl-N,N-dimethylammonium chloride (DODAC) and poly(ethylene glycol) (PEG) conjugated ceramides (PEG-Cer), employing a detergent dialysis procedure. These SPLP have potential as vectors for in viv...

Journal: :The Ulster Medical Journal 2007
Sharon Lowry Simon D Johnston

BACKGROUND Community follow-up is often inadequate for patients discharged from hospital following commencement of PEG tube feeding. OBJECTIVE AND METHODS We performed a postal questionnaire to assess if patients/carers were trained in the care of the PEG tube pre-discharge and whether appropriate community follow-up was in place. RESULTS Of 166 PEG tubes inserted during the study period, 6...

Journal: :The Journal of clinical endocrinology and metabolism 2000
C J Hukshorn W H Saris M S Westerterp-Plantenga A R Farid F J Smith L A Campfield

To assess the biological activity and tolerability of pegylated recombinant native human leptin (PEG-OB), 30 obese men (mean body mass index, 33.9 kg/m2) were randomized to a double-blind treatment with weekly sc injections of 20 mg PEG-OB or placebo for 12 weeks, in addition to a hypocaloric diet (deficit, 2 MJ/day). Body composition, energy expenditure, and metabolic parameters were measured ...

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