نتایج جستجو برای: pegylated interferon alfa

تعداد نتایج: 83792  

Journal: :Annals of hepatology 2012
Jaber Al-Ali Iqbal Siddique Rosh Varghese Fuad Hasan

BACKGROUND Approximately one-third of patients with chronic hepatitis C virus infection have persistently normal liver enzymes reflected by a normal serum alanine transaminase (ALT). Data with regards the efficacy and safety of treatment in patients chronically infected with Hepatitis C virus genotype 4 and normal serum ALT are limited. AIM To evaluate the efficacy and safety of peginterferon...

Journal: :Acta gastro-enterologica Belgica 2010
H Van Vlierberghe M Adler B Bastens I Colle J Delwaide J Henrion Y Horsmans P Michielsen P Golstein J-P Mulkay W Van Steenbergen P Yap F Nevens A M Denys J-P Brasseur

BACKGROUND AND STUDY AIMS Large international clinical trials conducted in the past 5 years rapidly improved the treatment of chronic hepatitis C; however, it is unclear whether the advances seen in clinical trials are being paralleled by similar improvements in routine clinical practice. PegIntrust is a Belgian community-based trial evaluating the sustained virological response. PATIENTS AND...

2016

Introduction: Serum transaminases rose significantly in 7 patients with chronic hepatitis C, genotypes 2 and 3, who were treated with pegylated interferon and ribavirin. Methods: 219 patients with chronic hepatitis C, genotypes 2 and 3, were treated between 2005 and 2011 following the same protocol. For the 7 patients presented in this paper, the initial liver screen revealed chronic hepatitis ...

Journal: :The New England journal of medicine 2003
Stephen G O'Brien François Guilhot Richard A Larson Insa Gathmann Michele Baccarani Francisco Cervantes Jan J Cornelissen Thomas Fischer Andreas Hochhaus Timothy Hughes Klaus Lechner Johan L Nielsen Philippe Rousselot Josy Reiffers Giuseppe Saglio John Shepherd Bengt Simonsson Alois Gratwohl John M Goldman Hagop Kantarjian Kerry Taylor Gregor Verhoef Ann E Bolton Renaud Capdeville Brian J Druker

BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic-phase chronic myeloid leukemia (CML) who have had no response to interferon alfa. We compared the efficacy of imatinib with that of interferon alfa combined with low-dose cytarabine in newly diagnosed chronic-phase CML. METHODS We randomly assigned 1106 patients to ...

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