نتایج جستجو برای: pentylenetetrazol
تعداد نتایج: 544 فیلتر نتایج به سال:
Background: Epilepsy is a chronic central nervous system disorder with high prevalence in modern society. Despite using common anticonvulsant drugs, its control not adequately achieved. Animal models for seizures play the leading role advancing our understanding of cellular mechanisms epilepsy. The present study was an attempt to elucidate electrophysiological mechanism effect sodium valproate ...
Epileptic seizures are a consequence of uncontrolled neuronal discharge and demand urgent prolonged treatment. Due to lack potent low-risk drugs that could prevent seizures, efforts underway discover new drugs, plant metabolites often considered valuable candidates in this search. Lemon balm ( Melissa officinalis L., Lamiaceae) is world-renowned medicinal affecting central nervous system functi...
In the present study, the effects of caerulein and CCK receptor antagonist< on tolerance to the anti-pentylenetetrazol activity of diazepam has been studied. Different doses of diazepam (20, 30, 35, 40 and 50 mg/kg) were administered intraperitoneally for a period of 6 days in order to induce tolerance to diazepam. 48 h after the last dose of diazepam, a test dose of diazepam was tested for...
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