نتایج جستجو برای: pepsinogens
تعداد نتایج: 310 فیلتر نتایج به سال:
BACKGROUND Northern Iran (Ardabil) is characterized by a high gastric cancer (GC) rate, whereas Southern Iran (Kerman and Yazd) has a low GC rate. The aim of this study is to verify the potential for pepsinogen I and II to detect atrophic gastritis (AG) in both high and low risk populations for GC. METHODS Sera of blood donors and patients with GC from Ardebil, Kerman and Yazd were used to me...
Background: Serologic screening of gastric cancer (GC) by serum pepsinogens (sPG) levels and Helicobacter pylori (Hp) sero-status, though highly informative, has provided heterogeneous results. Here, we have evaluated the modifying effects of demographic factors on the risk impact of Hp sero-status/sPG levels in gastric cancer, with particular emphasis on age. Methods: A cross-sectional study w...
background: serologic screening of gastric cancer (gc) by serum pepsinogens (spg) levels and helicobacter pylori (hp) sero-status, though highly informative, has provided heterogeneous results. here, we have evaluated the modifying effects of demographic factors on the risk impact of hp sero-status/spg levels in gastric cancer, with particular emphasis on age. methods: a cross-sectional study w...
BACKGROUND Previous studies have revealed the significance of Helicobacter pylori (H. pylori) infection as a risk factor of gastric cancer. Cytotoxin-associated gene A (cagA) positivity has been demonstrated to determine the clinical outcome of H. pylori infection in the presence of SHP-2 (src homology 2 domain-containing protein tyrosine phosphatase-2). This study aimed to examine the formerly...
A positive family history is a strong and consistently reported risk factor for gastric cancer (GC). So far, it has been demonstrated that serum pepsinogens (PGs), and gastrin 17 (G17) are useful for screening individuals at elevated risk to develop atrophic gastritis but they are suboptimal biomarkers to screen individuals for GC. The main purpose of this study was to investigate serum metabol...
BACKGROUND Despite the similar rate of HP infection, the rate of gastric cancer (GC) differs in different regions of the country. There are conflicting reports for using a panel of serologic tests such as pepsinogens I, II (PG I and PG II), and gastrin for population screening. We designed this study to assess healthy appearing adults in Shiraz, southern Iran in order to evaluate the correlatio...
Correspondence to: Kadir Ozturk Department of Gastroenterology, Gulhane School of Medicine, Etlik, Kecioren, Ankara 06010, Turkey Tel: +90-3123044045, Fax: +90-3123044047, E-mail: [email protected] Received on July 10, 2015. Accepted on August 1, 2015. Published online January 19, 2016 pISSN 1976-2283 eISSN 2005-1212 https://doi.org/10.5009/gnl15316 To the Editor, Gastric cancer is the ...
This study examined the efficacy and pharmacological mechanism of pronase-assisted low-dose antibiotics for eradication of Helicobacter pylori. Mongolian gerbils infected with H. pylori received 7-day treatment (omeprazole, different concentrations of pronase, amoxicillin, and clarithromycin), and the efficacy was assessed using the eradication rate and the colonization of H. pylori. In Mongoli...
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