نتایج جستجو برای: percutaneous absorption

تعداد نتایج: 187163  

Transdermal patches loaded with pravastatin was previously characterized in another published study by Serrano-Castañeda et al; 2015. These transdermal patches (TP) were generated by the plate casting technique, the in vitro percutaneous absorption studies of TP were evaluated for three different formulations of TP with different quantities of Pluronic F-127 (PF-127): i) without PF-127 (TP W), ...

Journal: :Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 1995

Journal: :Circulation. Cardiovascular interventions 2012
Juliane Jaitner Tanja Morath Robert A Byrne Siegmund Braun Daniela Gebhard Isabell Bernlochner Stefanie Schulz Julinda Mehilli Albert Schömig Werner Koch Adnan Kastrati Dirk Sibbing

BACKGROUND The prodrug clopidogrel requires intestinal absorption by the efflux pump P-glycoprotein MDR1 (multidrug resistant-1), encoded by the ABCB1 gene. Prior studies suggested that a common and functional genetic variant (C3435T, rs1045642) within ABCB1 influences clopidogrel treatment efficacy; however, existing data are highly inconsistent, because other studies failed to replicate this ...

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