Periodontitis is a major cause for tooth loss, which affects about 15% of the adult population. Cementum regeneration has been the crux of constructing the periodontal complex. Cementum protein 1 (CEMP1) is a cementum-specific protein that can induce cementogenic differentiation. In this study, poly(ethylene glycol) (PEG)-stabilized amorphous calcium phosphate (ACP) nanoparticles were prepared ...

background: recently, there has been interest in non‑mammalian collagen sources such as fish collagen in the development of biomatrices and scaffolds for periodontal regeneration. in the present study, a novel collagen barrier membrane of fish origin was assessed in the treatment ofperiodontal intra‑bony defects. materials and methods: ten systemically healthy chronic periodontitis patients hav...

autogenous tooth transplantation (att) is a simple and reasonable choice for replacing the missing teeth when a proper donor tooth is available. this report presents a case of successful att of a maxillary right third molar for replacement of mandibular right second molar with a concomitant endodontic-periodontal disease. the mandibular second molar was believed to be hopeless due to a severe d...

PURPOSE Obtaining an answer to the question whether autogenous bone in combination with PRP give a therapeutical effect in the form of periodontal ligament attachment regeneration. Defining the degree of elimination of a convenient environment for subgingival bacterial plaque by reduction of periodontal pocket depth and periodontitis. MATERIAL AND METHODS Twenty-six systematically healthy pat...

The occurrence of periodontal disease in the population is on the increase and the therapeutic means combine conventional mechanic treatment with antibiotics and guided tissue regeneration and guided osseous regeneration. The most frequently used antibiotics are penicillins and tetracyclines and their derivatives. Unfortunately, the occurrence of allergic reactions especially to penicillins, as...

This investigation was designed to evaluate the healing response to the laser-assisted new attachment procedure (LANAP). Eight patients presenting with 12 teeth predetermined to be surgically extracted were enrolled and consented to treatment with full-mouth LANAP therapy. LANAP surgical therapy consisted of a first pass with a 360-Μm fiber diameter, laser settings with verified output of 4.0 W...

Canonical Wnt signaling is important in tooth development but it is unclear whether it can induce cementogenesis and promote the regeneration of periodontal tissues lost because of disease. Therefore, the aim of this study is to investigate the influence of canonical Wnt signaling enhancers on human periodontal ligament cell (hPDLCs) cementogenic differentiation in vitro and cementum repair in ...

Periapical surgery aims to remove periapical pathology to achieve complete wound healing and regeneration of bone and periodontal tissue. Platelet rich fibrin (PRF) is a wonderful tissue engineering product and has gained much popularity due to its promising results in wound healing by bone induction. The features of this product are an attribute of platelet cells, which, after cellular interac...

Mineral Trioxide Aggregate is a material developed for endodontics that appears to be a significant improvement over other materials for procedures in bone. It is the first restorative material that allows for the overgrowth of cementum and the regeneration of periodontal ligament. The present case report illustrates the use of MTA in treating a case of perforation in the furcation area with lo...