نتایج جستجو برای: personalized treatment advanced
تعداد نتایج: 1620631 فیلتر نتایج به سال:
The influence of sex differences in movement disorders is still under-recognized. There are significant the pathophysiology, epidemiology, clinical manifestations, and treatments outcome many especially Parkinson’s disease. Importance specific invasive treatment outcomes emphasize importance their considering when devising patient’s individual management strategies. Increased recognition future...
Advanced personalized web applications require a carefully dealing with their users’ wishes and preferences. Since such preferences do not always hold in general, personalized applications also have to consider the user’s current situation. In this paper we present a novel framework for modeling situations and situated preferences. Our approach consists of a general meta model for situations, w...
BACKGROUND Diffuse large B-cell lymphoma (DLBCL) is the most common histology of non-Hodgkin lymphoma, representing 25% to 35% of new cases annually. The incidence of DLBCL has doubled in the past decades, highlighting the need for more effective treatment regimens. METHODS This article reviews the current protocols applicable to this aggressive lymphoma and discusses ongoing research that is...
PURPOSE The purpose of this study was to develop an integrated genomic-based approach to personalized treatment of patients with advanced-stage ovarian cancer. We have used gene expression profiles to identify patients likely to be resistant to primary platinum-based chemotherapy and also to identify alternate targeted therapeutic options for patients with de novo platinum-resistant disease. ...
Personalized medicine is the development of 'tailored' therapies that reflect traditional medical approaches, with the incorporation of the patient's unique genetic profile and the environmental basis of the disease. These individualized strategies encompass disease prevention, diagnosis, as well as treatment strategies. Today's healthcare workforce is faced with the availability of massive amo...
AIM To assess the efficacy and safety of a new treatment modality, cellular immune therapy based on personalized peptide vaccination (PPV-DC-CTL) combined with radiotherapy, for treating advanced hepatocellular carcinoma (HCC). METHODS A total of nine patients with advanced HCC were enrolled. Multidisciplinary consultation confirmed that all the patients definitely had no opportunity of surge...
Finding accurate methods to be employed for the treatment of esophageal cancers is of especial interest for researchers, due to the sensitivity of this tissue. Recently radioactive stents loaded with I-125 brachytherapy seeds have been widely investigated for the treatment of advanced esophageal cancer. It is necessary to investigate the dose distribution of any radioactive esophageal stents be...
Background: Rectal cancer is a significant healthcare burden, and effective treatment crucial. This research aims to compare the effectiveness of surgical endoscopic resection, transanal radiotherapy. Methods: A literature analysis was conducted in order identify relevant studies, by comparing different approaches variables affecting decisions. The findings were analyzed synthesized provide com...
To develop a peptide vaccine for cancer patients with the HLA-A26 allele, which is a minor population worldwide, we investigated the immunological responses of HLA-A26(+) /A26(+) cancer patients to four different CTL epitope peptides under personalized peptide vaccine regimens. In personalized peptide vaccine regimens, two to four peptides showing positive peptide-specific IgG responses in pre-...
Personalized medicine is a novel medical model with all decisions and practices being tailored to individual patients in whatever ways possible. In the era of genomics, personalized medicine combines the genetic information for additional benefit in preventive and therapeutic strategies. Personalized medicine may allow the physician to provide a better therapy for patients in terms of efficienc...
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