نتایج جستجو برای: pertussis
تعداد نتایج: 10564 فیلتر نتایج به سال:
Infants hospitalized for Bordetella pertussis infection commonly have respiratory viral coinfections
BACKGROUND Whether viral coinfections cause more severe disease than Bordetella pertussis (B. pertussis) alone remains unclear. We compared clinical disease severity and sought clinical and demographic differences between infants with B. pertussis infection alone and those with respiratory viral coinfections. We also analyzed how respiratory infections were distributed during the 2 years study....
BACKGROUND Recent studies worldwide have reported increasing numbers of adults diagnosed with Bordetella pertussis despite receiving childhood vaccinations. This study describes a pertussis outbreak at a university medical faculty campus and examines the effectiveness of diphtheria, tetanus, and pertussis (DTaP) vaccination completed during infancy in Japan. METHODS After the outbreak, self-a...
Clinical studies of component (“acellular”) pertussis vaccines have been undertaken in recent years, and several acellular vaccines have been used in Japan for 10 years. The Committee has reviewed these trials and related data and herein provides its assessment regarding the current status of the acellular vaccines and their possible use in the United States. The pertussis vaccines in current u...
A serological study to determine the frequency of Bordetella pertussis infection in 100 adults aged >/=65 years was carried out over a 3-year period. Ten serum samples (collected every 4 months) from each subject were examined for IgA and IgG antibodies to the following B. pertussis antigens: pertussis toxin (PT), filamentous hemagglutinin (FHA), pertactin, and fimbriae-2. A >/=2-fold titer inc...
I nfection with Bordetella pertussis, the cause of whooping cough, is common in the adult and adolescent population because immunity from prior illness or childhood vaccination is not lifelong. As many as 800,000 to 3.3 million cases of pertussis may occur annually in the United States. Because pertussis causes cough for prolonged periods of time, and the organism spreads readily from person to...
Pertussis is a highly infectious respiratory disease that is currently responsible for nearly 300,000 annual deaths worldwide, primarily in infants in developing countries. Despite sustained high vaccine uptake, a resurgence in pertussis incidence has been reported in a number of countries. This resurgence has led to critical questions regarding the transmission impacts of vaccination and pertu...
Since the introduction in 1998 of an adolescent pertussis vaccine booster (for persons aged 11-13 years) in France, the incidence of pertussis in adolescents and adults has been unknown. We therefore undertook a study to estimate the incidence of pertussis in these population groups and to evaluate the feasibility of a real-time electronic surveillance system for pertussis in general practices ...
Seroprevalence of Bordetella pertussis immunoglobulin G antibodies among children in Samsun, Turkey.
In this study, we aimed to investigate anti-pertussis immunoglobulin (Ig) G antibodies in the serum of children in our region vaccinated against pertussis with four doses. Between August 2008-2009, antibody levels to Bordetella pertussis (B. pertussis) antigens were studied in 385 serum samples from healthy children aged 1.5-18 years (y) vaccinated against pertussis in Samsun, Turkey. The study...
Whooping cough is considered a childhood disease, although there is growing evidence that children are infected by adult carriers. Additionally, increasing numbers of vaccinated adults are being diagnosed with Bordetella pertussis disease. Thus it is critical to understand how B. pertussis remains endemic even in highly vaccinated or immune populations. Here we used the mouse model to examine t...
Background and Aims: Pertussis is a highly contagious, vaccine-preventable disease. Determination of the seroepidemiology of pertussis makes possible the evaluation of pertussis immunity in a population. In this study, we determined the seroprevalence of Bordetella pertussis IgG antibodies in different age groups in Tehran, Iran. Materials and Methods: Overall, 1101 subjects between ages of 8 m...
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