Medical efforts and financial expenditures devoted to initial breast cancer staging represent a heavy burden on health care resources. Staging the disease accurately is considered to be important before surgery, in order to spare unnecessary treatment to patients with metastatic disease [1]. The role of 2-[fluorine-18]fluoro-2-deoxy-D-glucose–positron emission tomography (FDG-PET) in the stagin...

UNLABELLED The authors' goal was to show the importance of starting scanning at a uniform time after F-18 fluorodeoxyglucose injection in positron emission tomography (PET) brain study. METHOD Fifteen healthy normal subjects underwent FDG-PET to obtain glucose metabolic images starting 60 min and 70 min after FDG injection, respectively. The two sets of images were compared in a voxel-by-voxe...

OBJECTIVE The authors' goal was to determine whether FDG uptakes in various regions of the brain are different for early and late scanning time in positron emission tomography (PET). METHOD F-18 fluorodeoxyglucose (FDG) PET was performed on 15 healthy normal subjects to obtain early and late acquisition glucose metabolic images (30 and 60 min after FDG injection), respectively. The two sets o...

BACKGROUND In most malignant cells, the relatively low level of glucose-6-phosphatase leads to accumulation and trapping of [18F]fluorodeoxyglucose (FDG) intracellularly, allowing the visualization of increased uptake compared with normal cells. OBJECTIVES To assess the value of FDG positron emission tomography (PET) to differentiate benign from malignant hepatic lesions and to determine in w...

UNLABELLED Respiratory motion during PET acquisition may lead to blurring in resulting images and underestimation of uptake parameters. The advent of integrated PET/MR scanners allows us to exploit the integration of modalities, using high spatial resolution and high-contrast MR images to monitor and correct PET images degraded by motion. We proposed a practical, anatomy-independent MR-based co...

OBJECTIVE Angiomyolipoma is the most common benign kidney tumor. However, literature describing FDG PET findings on renal angiomyolipoma (AML) is limited. This study reports the FDG PET and PET/CT findings of 21 cases of renal AML. MATERIALS AND METHODS The study reviews FDG PET and PET/CT images of 21 patients diagnosed with renal AML. The diagnosis is based on the classical appearance of an...

Necrotizing fasciitis is a part of a spectrum of necrotizing soft tissue infections that usually follow a surgical intervention or a chronic / acute medical illness. Diagnosis is often based on symptoms which classically start within hours after an injury. There are no reports on the use of PET/CT in this condition. Sparing reports of its association in patients with malignancy (Ca of colon and...

Accumulation of [11C]flumazenil (FMZ) reflects central nervous system benzodiazepine receptor (BZR). We searched for the optimal time for a static PET scan with FMZ as semi-quantitative imaging of BZR distribution. In 10 normal subjects, a dynamic series of decay-corrected PET scans was performed for 60 minutes, and the arterial blood was sampled during the scan to measure radioactivity and lab...