Conventional optical nanoparticle pH sensors that are designed for ratiometric measurements in cells have been based on utilizing one sensor fluorophore and one reference fluorophore in each nanoparticle, which results in a relatively narrow dynamic measurement range. This results in substantial challenges when conducting live cell measurements, which often leads to misleading results. In the p...

Gastrointestinal (GI) pH has been measured in 66 normal subjects using a pH sensitive radiotelemetry capsule passing freely through the gastrointestinal tract. Signals were recorded with a portable solid state receiver and recording system, enabling unconstrained measurements with normal ambulatory activities for up to 48 h during normal GI transit. Capsule position in the gut was monitored by ...

BACKGROUND pH is known as an important parameter in epidermal barrier function and homeostasis. AIM The impact of age and body site on skin surface pH (pH(SS)) of women was evaluated in vivo. METHODS Time domain dual lifetime referencing with luminescent sensor foils was used for pH(SS) measurements. pH(SS) was measured on the forehead, the temple, and the volar forearm of adult females (n ...

Enzyme sensors based on the measurement of pH consist basically of a pH-sensitive electrode to which an enzyme-loaded membrane is attached. The conversion of substrate in the immobilized enzyme membrane results in a local change in pH which can then be measured. The pH-sensitive electrode used is usually a glass membrane electrode or an ISFET. In 1980, Caras and Janata [l] described the first I...

Metabolic acidosis is defined as a low arterial blood pH in conjunction with a reduced serum HCO3concentration. Respiratory compensation results in a decrease in PaCO2. A low serum HCO3concentration alone is not diagnostic of metabolic acidosis because it also results from the renal compensation to chronic respiratory alkalosis. Measurement of the arterial pH differentiates between these two po...

We developed photo-induced selective injection of nanotool into a specific cell for intracellular measurement in a microfluidic chip. We used membrane fusion of the liposome for invasive cell injection of the nanotool. The nanotool was modified by photo-responsive chemical for pH control and fluorescent dye for environment measurement. The nanotool was included in fusogenic liposome. Fusion-cap...

We report on the characterisation of pH-responsive polyelectrolyte microcapsules based on the measurement of their electrical impedance. A microfabricated impedance spectrometer was used to measure the properties of individual capsules. We show the ability of the system to discriminate between different capsule compositions and detect changes in size and dielectric properties of pH responsive m...

The object is to control the pH of the “salt cake solution” before it is sent to the chemical recovery system. This is to prevent the formation of H2S gas. The formation of H2S gas can be extremely dangerous in the Mill environment. Further, H2S is routinely monitored in Pulp & Paper Mills to comply with federal, state and provincial regulations. In this particular application, the pH measureme...

typed double-spaced (including references) with conventional margins. The overall length is limited to five manuscript pages, including not more than one figure or one table. To the Editor: Ionized calcium is now the measurement of choice for evaluating calcium metabolic diseases (1, 2). Ionized calcium may be reported either as the actual ionized calcium, referred to the actual pH of the patie...