metastatic survey of the patients with known primary malignancies with bone scan is one of the most common studies in nuclear medicine. unfortunately the conventional planar bone scan has a very low specificity for differentiating benign from malignant lesions especially in the spinal column. in this study, we compared the specificity of spect imaging and conventional planar bone scan. we studi...

Introduction SPECT projections are contaminated by scatter radiation, resulting in reduced image contrast and quantitative errors. Backscatter constitutes a major part of the scatter contamination in lower energy windows. The current study is an evaluation of the effect of backscatter material on FWHM and image quality investigated by Monte Carlo simulation. Materials and Methods SIMIND program...

The Institute of Nuclear Medicine, University College London, London, UK This project’s goal is to design a SPECT insert for a clinical MRI system for simultaneous brain SPECT/MR imaging. We assume the stationary SPECT insert will consist of two rings of ∼5x5-cm SiPM-based detectors insensitive to magnetic fields, with 0.8-mm intrinsic resolution. The maximum diameter is 44.5 cm, the minimum di...

Purpose MRI and single-photon emission computed tomography (SPECT) provide complimentary information which could aid in the diagnosis of various diseases. However, acquiring images from both modalities can been problematic. Until recently, SPECT systems could not be integrated with MRI systems due to the use of photomultiplier tubes which do not function in high magnetic fields. The development...

The need to study dynamic biologic processes in intact small-animal models of disease has stimulated the development of high-resolution nuclear imaging methods. These methods are capable of clarifying molecular interactions important in the onset and progression of disease, assessing the biologic relevance of drug candidates and potential imaging agents, and monitoring therapeutic effectiveness...

  Metastatic survey of the patients with known primary malignancies with bone scan is one of the most common studies in nuclear medicine. Unfortunately the conventional planar bone scan has a very low specificity for differentiating benign from malignant lesions especially in the spinal column. In this study, we compared the specificity of SPECT imaging and convention...

OBJECTIVES Dopamine transporter imaging with single-photon emission computed tomography (SPECT) is a valuable tool for both clinical routine and research studies. Recently, it was found that the image quality could be improved by introduction of the three-dimensional ordered subset expectation maximization (3D-OSEM) reconstruction algorithm, which provides resolution recovery. The aim of this s...

P. R. Seevinck, J-H. Seppenwoolde, T. C. de Wit, J. F. Nijsen, F. J. Beekman, A. D. van het Schip, C. J. Bakker Image Sciences Institute, University Medical Center, Utrecht, Netherlands, Department of Nuclear Medicine, University Medical Center, Utrecht, Netherlands Introduction A distinct trend in image-guided treatment is the integration of imaging modalities and the development of dedicated ...