: For the determination of ketoconazole in bulk and pharmaceutical dosage form accordance with ICH guidelines, a new, economical, precise, sensitive, linear, accurate, quick UV-Spectrophotometric approach has been developed Methylene chloride. The UV-visible spectrum Ketoconazole was examined to determine its maximum absorption wavelength that is λ max at 255.2 nm. Linearity, accuracy, precisio...

In recent years, in association with progress and innovation in the field of pharmaceutical technology, there has been an increasing effort to develop prolonged release dosage forms for many drugs. Correspondingly, a growing number of new prolonged release dosage forms have been submitted for regulatory approval. Prolonged release dosage forms have many advantages in safety and efficacy over im...

The pharmaceutical excipients used for oral dosage form have been traditionally assumed as being inert. However, recent studies have shown that they can interact with the active drug ingredient, affecting its dissolution, absorption and bioavailability. Beyond the dosage form necessities, excipients are required to perform important and specific technological functions, particularly in the case...