An ideal drug delivery system will possess three main properties: (a) It will be a single dose for the whole duration of treatment. (b) It will deliver the active drug directly at the site of action. (c) It will possess possible fewer side effects. Above approaches are achieved with the help of suitable choice of polymer. When it comes to targeted drug release profiles, Eudragit is the pharmace...

Introduction The dissolution test as defined in the United States Pharmacopoeia (1) is used in judging the quality of pharmaceutical products. Dissolution testing is a method for evaluating physiological availability that depends upon having the drug in a dissolved state. The USP Dissolution testing involves three stages and the acceptance criteria are defined for each stage as a function of a ...

Poor solubility of active pharmaceutical ingredients (APIs) is a great challenge for the pharmaceutical industry and, hence, drug nanocrystals are widely studied as one solution to overcome these solubility problems. Drug nanocrystals have comparatively simple structures which make them attractive for the formulation for poorly soluble drugs, and their capability to improve the dissolution in v...

Solid dose drugs comprise a considerable segment of the pharmaceutical market. The solid dose form can offer long shelf life, convenient drug delivery, and can be packaged into capsules, tablets, gel caps, and patches. Polymorphism is the ability of a molecule to exist in more than one stable or meta-stable crystalline state. Distinct crystalline forms commonly exhibit differences in pharmacolo...

Tamarind seed polysaccharide (TSP) obtained from the seed kernel of Tamarindus indica, possesses properties like high viscosity mucilage, broad pH tolerance, no carcinogenicity, mucoadhesive nature, and biocompatibility. It is used as stabilizer, thickener, gelling agent, and binder in food and pharmaceutical industries. The objective of present investigation was to search for a cheap and effec...

Pharmaceutical and biotech research often involves discovering new properties of, or new methods to use, existing compositions. The doctrine of inherent anticipation, however, prevents the issuance and/or validity of a patent for discoveries deemed to have been implicitly disclosed in the prior art. This can be a barrier to patent rights in these technologies. Inherent anticipation therefore cr...

Drug delivery technologies have the potential to enable drug candidates with poor pharmaceutical or biopharmaceutical properties, both for macromolecule and traditional compounds. While there have been many success stories to date, the future offers even more promise. In this article, the author surveys the top ten areas in drug delivery looking forward. William J. Lambert, PhD, is the senior v...

Aromatic plants have subscribed to the belief that they can be used in food, perfumery, pharmaceutical and cosmetic products due to their nutritional and biological properties. The present study was designed to examine the chemical composition and antibacterial and analgesic properties of Lavandula stoechas flowers originating Amol, north of Iran for the first time. The essential oil o...

Ion exchange resins (IER) are cross-linked, water insoluble polymers carrying ionizable functional groups on their repeating positions. They are considered as safe materials due to their insoluble and nonabsorbable nature. This advantage made IER subject of several research in different areas of pharmaceutical technology such as oral sustained release, taste masking, rapid dissolution, stabilit...

From long time, scientists are looking for natural biomolecules in order to discover new pharmaceutical agents. Therefore polysaccharides which are natural molecules from several biotopes (microbial, plant, algae, fungi, animals, and insects) constitute a very large potential of application for medical treatment. Among them, chitosan a deacetylated form of chitin (one of the most abundant polys...