This paper proposes a single-phase seven-level inverter for grid-connected photovoltaic systems, with a novel pulse width-modulated (PWM) control scheme. Three reference signals that are identical to each other with an offset that is equivalent to the amplitude of the triangular carrier signal were used to generate the PWM signals. The inverter is capable of producing seven levels of output-vol...

The purpose of this study is to evaluate the primary mechanism through which interferon (IFN)-beta exhibits target-mediated drug disposition (TMDD) and whether the theoretical assumptions of TMDD models are consistent with experimental pharmacokinetic (PK) data. Recombinant murine IFN-beta was administered as an intravenous injection at two dose levels (0.5 and 1 million IU/kg) to male wild-typ...

and Implications Pre-ruminant Holstein bull calves were fed two diets of pasteurized whole milk (PWM) in amounts that either limited intake or that maximized intake according to common commercial practice. Diets then were either supplemented or not supplemented with a full complement of vitamins and trace minerals (VTM) that met or exceeded NRC requirements. The objective of the study was to qu...

This paper presents a single-phase five-level photovoltaic (PV) inverter topology for grid-connected PV systems with a novel pulse width-modulated (PWM) control scheme. Two reference signals identical to each other with an offset equivalent to the amplitude of the triangular carrier signal were used to generate PWM signals for the switches. The inverter offers much less total harmonic distortio...

Erythropoietin (EPO) has a highly conserved structure among mammals, and thus recombinant human EPO (rHuEPO) has biological activity in various species. This study explores the interspecies relationships of the pharmacokinetics (PK) and pharmacodynamics (PD) of rHuEPO. The PK parameters such as clearance (CL) and volume of distribution (V(ss)) after i.v. doses of rHuEPO were obtained in several...

The need for high power apparatus in industry has increased in recent years. Multilevel inverters have developed as easy alternatives for such power requirements. Multilevel inverters consist of a group of semiconductor switches and a set of voltage source components like capacitors or independent sources. The basic concept of these inverters depends on using this series of switches and sources...

A mechanism-based pharmacokinetic-pharmacodynamic (PK/PD) model was developed for exendin-4 to account for receptor-mediated endocytosis via GLP-1 receptor (GLP-1R) as the primary mechanism for its nonlinear disposition. Time profiles of exendin-4 concentrations following intravenous (iv), subcutaneous (sc) and continuous iv infusion doses in rats, iv and sc doses in monkeys, and iv infusion an...

This paper proposes a single-phase seven-level inverter for grid-connected photovoltaic systems, with a novel pulse width-modulated (PWM) control scheme. Three reference signals that are identical to each other with an offset value that is equivalent to the amplitude of the triangular carrier signal were used to generate the PWM signals. The inverter is capable of producing seven levels of outp...

Recently, the evolution of single phase multilevel inverters has been escalation due to its preference over traditional one. In this paper proposed a new topology of single phase Nine level inverter with less number of power elements for grid connection. In this proposed inverter have ten switches and their switches operate with fundamental frequency. The proposed inverter produced nine level o...

This paper presents a novel single-phase high-powerfactor (HPF) pulsewidth-modulated (PWM) boost rectifier featuring soft commutation of the active switches at zero current (ZC). It incorporates the most desirable properties of conventional PWM and soft-switching resonant techniques. The input current shaping is achieved with average current mode control and continuous inductor current mode. Th...