Diseases of the central nervous system continue to catalyse dealmaking as companies search for new therapies tackle some major unmet medical needs.

An empirical correlation, based on conventional forms, has been developed to represent the oxygen mass transfer coefficient as a function of operating conditions and organic fraction in two-phase, aqueous-organic dispersions. Such dispersions are characteristic of two-phase partitioning bioreactors, which have found increasing application for the biodegradation of toxic substrates. In this work...

The structures of isoenzymes differ and yet these catalyse the same type of reaction. These structures evolved to suit the physiological needs and are located in different parts of cells or tissues. Moonlighting proteins represent the same structure performing very different biological functions. Biological promiscuity reveals that the same active sites can catalyse different types of reactions...

Microsomal preparations from rat adipose tissue catalyse the transfer of [(14)C]mannose from GDP-[(14)C]mannose to an endogenous acceptor forming a [(14)C]mannosyl lipid. The mannosyl lipid co-chromatographs with hen oviduct dolichyl monophosphate beta-mannose on three solvent systems. It is stable to mild alkaline hydrolysis, but strong alkaline treatment yields a compound that co-migrates wit...

This paper investigate the results of distributing the delay of a single feedback system. To distribute the delayed feedback, the single delay is replaced by the sum of two distinct delays with the same e↵ective delay. The statistical properties of the new distribution function in the feedback, namely the sum of two delta functions, are used to quantify the e↵ectiveness of delay distribution. W...

The dynamics of the optically induced phase transition from the antiferromagnetic to the paramagnetic state in FeBO3 is observed using a pump-probe magneto-optical Faraday technique employing 100 fs laser pulses. At the pump energy of 1.55 eV phonon-assisted transitions dominate in the absorption of light and ultrafast heating of the lattice occurs. The quenching of the magnetic order is caused...