Using a common 1-(1-phenylethenyl)-1,2,3,4-tetrahydroisoquinoline precursor to the required ylide or N-oxide intermediate, the Stevens [2,3] and analogous Meisenheimer [2,3] sigmatropic rearrangements have been applied to afford concise syntheses of phenyl -substituted representatives of each of the reduced 1H-3-benzazonine and 4,3-benzoxazonine systems, respectively. Single crystal X-ray struc...

The MetalJet X-ray source provides indium K α radiation with a wavelength even shorter than Ag radiation. This paper reports on problematic spectral impurities and presents possible countermeasures so that collection of data excellent quality up to high resolution is possible. It demonstrated these can be used in the refinement multipole model, results which are for topological analysis assess ...

The importance of chiral epoxides as synthetic building blocks in asymmetric synthesis is extremely difficult to overstate. While the highly enantioselective Sharpless, and JacobsenKatsuki, protocols for the epoxidation of internal alkenes are nowmature technologies of inestimable value, the conversion of terminal alkenes to enantioenriched 1-oxiranes has proven a considerably more difficult pr...

Aryl chalcones rearrange and add methanol to give substituted propane-1-ones upon UV-A irradiation in the presence of PPh3. We propose two possible mechanisms for this photo-rearrangement. The reaction involves either the formation of a phosphine-carbonyl intermediate, nucleophilic addition of MeOH and 1,2-aryl migration or the formation of ylide and carbene intermediates. The intermediates tra...

We have devised a highly regio- and enantioselective iridium-catalyzed allylic amination reaction with the sulfur-stabilized aza-ylide, S,S-diphenylsulfilimine. This process provides a robust and scalable method for the construction of aryl-, alkyl- and alkenyl-substituted C-chiral allylic sulfilimines, which are important functional groups for organic synthesis. Additionally, the combination o...