The localisation of apico-basal polarity proteins along the Z-axis of epithelial cells is well understood while their distribution in the plane of the epithelium is poorly characterised. Here we provide a systematic description of the planar localisation of apico-basal polarity proteins in the Drosophila ommatidial epithelium. We show that the adherens junction proteins Shotgun and Armadillo, a...

A new and efficient method based on the simple metalating reagent Fe(CO)5 has been developed for the straightforward synthesis of well defined cyclometalled PCP iron carbonyl pincer complexes. The reaction proceeds cleanly under mild conditions at 30 °C and UV irradiation. Four hydride pincer complexes are synthesized and fully characterized as well as an intermediate dinuclear species. The new...

In order to model exposure to ingredients contained in personal care products (PCPs) and assess their potential risks to human health, access to reliable PCP use data, including co-use patterns, is essential. A postal questionnaire survey was conducted to determine the use patterns of eight leave-on PCP categories among the German-speaking population of Switzerland (N = 1,196; ages 0-97 years),...

The extracellular enzymes and cell mass from the pregrown Phanerochaete chrysosporium cultures were used for the degradation of PCP. The use of both extracellular enzymes and cell mass resulted in extensive mineralization of PCP, while the action of only the crude extracellular enzymes led to the formation of a degradation intermediate (TCHD). A kinetic model, which describes the relationship a...

The current proof of the PCP Theorem (i.e., N P = PCP(log; O(1))) is very complicated. One source of diiculty is the technically involved analysis of low-degree tests. Here, we refer to the diiculty of obtaining strong results regarding low-degree tests; namely, results of the type obtained and used by Arora and Safra and Arora et. al. In this paper, we eliminate the need to obtain such strong ...

PCP or phencyclidine was discovered in 1956 and soon became a popular street drug. Dissociatives including PCP, ketamine, and dextromethorphan have been used non-medically for their mind-altering effects for over 60 years. Many of these compounds have also been used clinically and in legitimate research. At least 14 derivatives of PCP were sold for non-medical and illict use from the late 1960s...